Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK047514-04
Application #
2016751
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1993-09-30
Project End
1997-08-31
Budget Start
1996-09-16
Budget End
1997-08-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Pathology
Type
Schools of Veterinary Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Mannikarottu, Anita S; Changolkar, Arun K; Disanto, Michael E et al. (2005) Over expression of smooth muscle thin filament associated proteins in the bladder wall of diabetics. J Urol 174:360-4
Changolkar, Arun K; Hypolite, Joseph A; Disanto, Michael et al. (2005) Diabetes induced decrease in detrusor smooth muscle force is associated with oxidative stress and overactivity of aldose reductase. J Urol 173:309-13
Hypolite, J A; DiSanto, M E; Zheng, Y et al. (2001) Regional variation in myosin isoforms and phosphorylation at the resting tone in urinary bladder smooth muscle. Am J Physiol Cell Physiol 280:C254-64
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Wang, Z; Yang, Z Q; Chacko, S (1997) Functional and structural relationship between the calmodulin-binding, actin-binding, and actomyosin-ATPase inhibitory domains on the C terminus of smooth muscle caldesmon. J Biol Chem 272:16896-903
DiSanto, M E; Cox, R H; Wang, Z et al. (1997) NH2-terminal-inserted myosin II heavy chain is expressed in smooth muscle of small muscular arteries. Am J Physiol 272:C1532-42
Chacko, S; DiSanto, M; Wang, Z et al. (1997) Contractile protein changes in urinary bladder smooth muscle during obstruction-induced hypertrophy. Scand J Urol Nephrol Suppl 184:67-76

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