Benign Bladder Disease and Mitochondrial Function

Hudson, Alan Paul

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 7R01DK047949-03
• Application #: 2713386
• Study Section: Surgery, Anesthesiology and Trauma Study Section (SAT)
• Project Start: 1996-07-26
• Project End: 2000-06-30
• Budget Start: 1997-09-01
• Budget End: 1998-06-30
• Support Year: 3
• Fiscal Year: 1997

Institution

• Name: Wayne State University
• Department: Microbiology/Immun/Virology
• Type: Schools of Medicine
• City: Detroit
• State: MI
• Country: United States
• Zip Code: 48202

Publications

Levin, Robert M; Hudson, Alan P (2004) The molecular genetic basis of mitochondrial malfunction in bladder tissue following outlet obstruction. J Urol 172:438-47

Ghafar, Mohamed A; Anastasiadis, Aristotelis G; Olsson, L Eric et al. (2002) Hypoxia and an angiogenic response in the partially obstructed rat bladder. Lab Invest 82:903-9

Ghafar, Mohamed A; Shabsigh, Ahmad; Chichester, Paul et al. (2002) Effects of chronic partial outlet obstruction on blood flow and oxygenation of the rat bladder. J Urol 167:1508-12

Wu, Xingyao; Wang, Zhao; Levin, Robert M et al. (2002) Cloning of COX4 cDNA from the NZ white rabbit and expression of this gene in bladder smooth muscle following partial outlet obstruction. World J Urol 20:255-9

Schroder, A; Kogan, B A; Lieb, J et al. (2001) Increased blood flow after catheterization and drainage in the chronically obstructed rabbit urinary bladder. Urology 58:295-300

Schroeder, A; Lieb, J; O'Connor, L et al. (2001) Role of calcium and calcium modulation in the control of urethral tone. Scand J Urol Nephrol Suppl :19-25; discussion 106-25

Bratslavsky, G; Kogan, B; Levin, R M (2001) Urethra is more sensitive to ischemia than bladder: evidence from an in vitro rat study. J Urol 165:2086-90

Schroder, A; Levin, R M; Kogan, B A et al. (2001) Aspirin treatment improves bladder function after outlet obstruction in rabbits. Urology 58:608-13

Wang, Z; Wu, X; Levin, R M et al. (2001) Loss of mitochondrial DNA in rabbit bladder smooth muscle following partial outlet obstruction results from lack of organellar DNA replication. Mol Urol 5:99-104

Parekh, M H; Lobel, R; O'Connor, L J et al. (2001) Protective effect of vitamin E on the response of the rabbit bladder to partial outlet obstruction. J Urol 166:341-6