Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK048071-03
Application #
2148124
Study Section
Endocrinology Study Section (END)
Project Start
1994-04-01
Project End
1999-03-31
Budget Start
1996-06-10
Budget End
1997-03-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
City
Evanston
State
IL
Country
United States
Zip Code
60201
McElvaine, Allison T; Mayo, Kelly E (2006) A dominant-negative human growth hormone-releasing hormone (GHRH) receptor splice variant inhibits GHRH binding. Endocrinology 147:1884-94
Cunha, Shane R; Mayo, Kelly E (2002) Ghrelin and growth hormone (GH) secretagogues potentiate GH-releasing hormone (GHRH)-induced cyclic adenosine 3',5'-monophosphate production in cells expressing transfected GHRH and GH secretagogue receptors. Endocrinology 143:4570-82
Lee, E J; Kotlar, T J; Ciric, I et al. (2001) Absence of constitutively activating mutations in the GHRH receptor in GH-producing pituitary tumors. J Clin Endocrinol Metab 86:3989-95
Voss, T C; Goldman, L R; Seek, S L et al. (2001) GH mRNA levels are elevated by forskolin but not GH releasing hormone in GHRH receptor-expressing MtT/S somatotroph cell line. Mol Cell Endocrinol 172:125-34
Mayo, K E; Miller, T; DeAlmeida, V et al. (2000) Regulation of the pituitary somatotroph cell by GHRH and its receptor. Recent Prog Horm Res 55:237-66; discussion 266-7
Miller, T L; Godfrey, P A; Dealmeida, V I et al. (1999) The rat growth hormone-releasing hormone receptor gene: structure, regulation, and generation of receptor isoforms with different signaling properties. Endocrinology 140:4152-65
Gaylinn, B D; Dealmeida, V I; Lyons Jr, C E et al. (1999) The mutant growth hormone-releasing hormone (GHRH) receptor of the little mouse does not bind GHRH. Endocrinology 140:5066-74
DeAlmeida, V I; Mayo, K E (1998) Identification of binding domains of the growth hormone-releasing hormone receptor by analysis of mutant and chimeric receptor proteins. Mol Endocrinol 12:750-65
Miller, T L; Mayo, K E (1997) Glucocorticoids regulate pituitary growth hormone-releasing hormone receptor messenger ribonucleic acid expression. Endocrinology 138:2458-65