Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
1R01DK048642-01A1
Application #
2149035
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1996-06-01
Project End
2000-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Hu, Yu-Long; Passegue, Emmanuelle; Fong, Stephen et al. (2007) Evidence that the Pim1 kinase gene is a direct target of HOXA9. Blood 109:4732-8
Bijl, Janet; Thompson, Alexander; Ramirez-Solis, Ramiro et al. (2006) Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells. Blood 108:116-22
Ferrell, Christina M; Dorsam, Sheri T; Ohta, Hideaki et al. (2005) Activation of stem-cell specific genes by HOXA9 and HOXA10 homeodomain proteins in CD34+ human cord blood cells. Stem Cells 23:644-55
Lawrence, H Jeffrey; Christensen, Julie; Fong, Stephen et al. (2005) Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells. Blood 106:3988-94
Fischbach, Neal A; Rozenfeld, Sofia; Shen, Weifang et al. (2005) HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo. Blood 105:1456-66
Pineault, Nicolas; Abramovich, Carolina; Ohta, Hideaki et al. (2004) Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1. Mol Cell Biol 24:1907-17
Dorsam, Sheri Tinnell; Ferrell, Christina M; Dorsam, Glenn P et al. (2004) The transcriptome of the leukemogenic homeoprotein HOXA9 in human hematopoietic cells. Blood 103:1676-84
Schneider, T E; Barland, C; Alex, A M et al. (2003) Measuring stem cell frequency in epidermis: a quantitative in vivo functional assay for long-term repopulating cells. Proc Natl Acad Sci U S A 100:11412-7
Pineault, Nicolas; Buske, Christian; Feuring-Buske, Michaela et al. (2003) Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1. Blood 101:4529-38
Buske, Christian; Feuring-Buske, Michaela; Abramovich, Carolina et al. (2002) Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells. Blood 100:862-8

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