Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK048744-02
Application #
2149179
Study Section
Medical Biochemistry Study Section (MEDB)
Project Start
1995-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Ohio State University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Chen, Q; Yin, F Q; Sprecher, H (2000) The questionable role of a microsomal delta8 acyl-coA-dependent desaturase in the biosynthesis of polyunsaturated fatty acids. Lipids 35:871-9
Sprecher, H (2000) Metabolism of highly unsaturated n-3 and n-6 fatty acids. Biochim Biophys Acta 1486:219-31
Sprecher, H; Chen, Q (1999) Polyunsaturated fatty acid biosynthesis: a microsomal-peroxisomal process. Prostaglandins Leukot Essent Fatty Acids 60:317-21
Sprecher, H; Chen, Q; Yin, F Q (1999) Regulation of the biosynthesis of 22:5n-6 and 22:6n-3: a complex intracellular process. Lipids 34 Suppl:S153-6
Yin, F Q; Chen, Q; Sprecher, H (1999) A comparison of the metabolism of [3-14C]-labeled 22- and 24-carbon (n-3) and (n-6) unsaturated fatty acids by rat testes and liver. Biochim Biophys Acta 1438:63-72
Chen, Q; Luthria, D L; Sprecher, H (1998) Analysis of the acyl-CoAs that accumulate during the peroxisomal beta-oxidation of arachidonic acid and 6,9,12-octadecatrienoic acid. Arch Biochem Biophys 349:371-5
Mohammed, B S; Luthria, D L; Bakousheva, S P et al. (1997) Regulation of the biosynthesis of 4,7,10,13,16-docosapentaenoic acid. Biochem J 326 ( Pt 2):425-30
Luthria, D L; Chen, Q; Sprecher, H (1997) Metabolites produced during the peroxisomal beta-oxidation of linoleate and arachidonate move to microsomes for conversion back to linoleate. Biochem Biophys Res Commun 233:438-41
Luthria, D L; Sprecher, H (1997) Studies to determine if rat liver contains multiple chain elongating enzymes. Biochim Biophys Acta 1346:221-30
Luthria, D L; Mohammed, B S; Sprecher, H (1996) Regulation of the biosynthesis of 4,7,10,13,16,19-docosahexaenoic acid. J Biol Chem 271:16020-5