Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
1R01DK048871-01A2
Application #
2149372
Study Section
General Medicine B Study Section (GMB)
Project Start
1996-04-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
O'Rourke, D A; Liu, Z X; Sellin, L et al. (2000) Hepatocyte growth factor induces MAPK-dependent formin IV translocation in renal epithelial cells. J Am Soc Nephrol 11:2212-21
Roshan, B; Kjelsberg, C; Spokes, K et al. (1999) Activated ERK2 interacts with and phosphorylates the docking protein GAB1. J Biol Chem 274:36362-8
O'Rourke, D A; Sakurai, H; Spokes, K et al. (1999) Expression of c-ret promotes morphogenesis and cell survival in mIMCD-3 cells. Am J Physiol 276:F581-8
Rameh, L E; Rhee, S G; Spokes, K et al. (1998) Phosphoinositide 3-kinase regulates phospholipase Cgamma-mediated calcium signaling. J Biol Chem 273:23750-7
Bae, Y S; Cantley, L G; Chen, C S et al. (1998) Activation of phospholipase C-gamma by phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 273:4465-9
Joannidis, M; Cantley, L G; Spokes, K et al. (1997) Modulation of c-fos and egr-1 expression in the isolated perfused kidney by agents that alter tubular work. Kidney Int 52:130-9
Sakurai, H; Tsukamoto, T; Kjelsberg, C A et al. (1997) EGF receptor ligands are a large fraction of in vitro branching morphogens secreted by embryonic kidney. Am J Physiol 273:F463-72
Derman, M P; Toker, A; Hartwig, J H et al. (1997) The lipid products of phosphoinositide 3-kinase increase cell motility through protein kinase C. J Biol Chem 272:6465-70