Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK049049-08
Application #
6380942
Study Section
Reproductive Endocrinology Study Section (REN)
Program Officer
Blondel, Olivier
Project Start
1994-09-30
Project End
2002-08-31
Budget Start
2001-09-01
Budget End
2002-08-31
Support Year
8
Fiscal Year
2001
Total Cost
$219,290
Indirect Cost
Name
Lawrence Berkeley National Laboratory
Department
Biochemistry
Type
Organized Research Units
DUNS #
078576738
City
Berkeley
State
CA
Country
United States
Zip Code
94720
Atlas, Ella; Cardillo, Marina; Mehmi, Inderjit et al. (2003) Heregulin is sufficient for the promotion of tumorigenicity and metastasis of breast cancer cells in vivo. Mol Cancer Res 1:165-75
Tsai, Miaw-Sheue; Shamon-Taylor, Lisa A; Mehmi, Inderjit et al. (2003) Blockage of heregulin expression inhibits tumorigenicity and metastasis of breast cancer. Oncogene 22:761-8
Tsai, Miaw-Sheue; Bogart, Daphne F; Li, Patricia et al. (2002) Expression and regulation of Cyr61 in human breast cancer cell lines. Oncogene 21:964-73
Tsai, Miaw-Sheue; Bogart, Daphne F; Castaneda, Jessica M et al. (2002) Cyr61 promotes breast tumorigenesis and cancer progression. Oncogene 21:8178-85
Tsai, M S; Hornby, A E; Lakins, J et al. (2000) Expression and function of CYR61, an angiogenic factor, in breast cancer cell lines and tumor biopsies. Cancer Res 60:5603-7
Hijazi, M M; Thompson, E W; Tang, C et al. (2000) Heregulin regulates the actin cytoskeleton and promotes invasive properties in breast cancer cell lines. Int J Oncol 17:629-41
Liu, W M; Guerra-Vladusic, F K; Kurakata, S et al. (1999) HMG-I(Y) recognizes base-unpairing regions of matrix attachment sequences and its increased expression is directly linked to metastatic breast cancer phenotype. Cancer Res 59:5695-703
Guerra-Vladusic, F K; Scott, G; Weaver, V et al. (1999) Constitutive expression of Heregulin induces apoptosis in an erbB-2 overexpressing breast cancer cell line SKBr-3. Int J Oncol 15:883-92