Lipid and (R)-3-Hydroxybutyrate Dehydrogenase

McIntyre, James Oliver

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 1R01DK049186-01A1
• Application #: 2149813
• Study Section: Biophysical Chemistry Study Section (BBCB)
• Project Start: 1996-06-01
• Project End: 2000-04-30
• Budget Start: 1996-06-01
• Budget End: 1997-04-30
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: Vanderbilt University Medical Center
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 004413456
• City: Nashville
• State: TN
• Country: United States
• Zip Code: 37212

Publications

Chelius, D; Loeb-Hennard, C; Fleischer, S et al. (2000) Phosphatidylcholine activation of human heart (R)-3-hydroxybutyrate dehydrogenase mutants lacking active center sulfhydryls: site-directed mutagenesis of a new recombinant fusion protein. Biochemistry 39:9687-97

Loeb-Hennard, C; McIntyre, J O (2000) (R)-3-hydroxybutyrate dehydrogenase: selective phosphatidylcholine binding by the C-terminal domain. Biochemistry 39:11928-38

Picklo, M J; Amarnath, V; McIntyre, J O et al. (1999) 4-Hydroxy-2(E)-nonenal inhibits CNS mitochondrial respiration at multiple sites. J Neurochem 72:1617-24