Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK049358-03
Application #
2150074
Study Section
Diabetes, Endocrinology and Metabolic Diseases B Subcommittee (DDK)
Project Start
1994-09-30
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Novak, Jan; Vu, Huong L; Novak, Lea et al. (2002) Interactions of human mesangial cells with IgA and IgA-containing immune complexes. Kidney Int 62:465-75
Matousovic, K; Konecny, K; Myystecky, J et al. (2002) [IgA nephropathy. Significance of immunoglobulin A glycosylation in pathogenesis and clinical presentation] Cas Lek Cesk 141:729-34
Novak, J; Julian, B A; Tomana, M et al. (2001) Progress in molecular and genetic studies of IgA nephropathy. J Clin Immunol 21:310-27
Takahashi, T; Iwase, T; Tachibana, T et al. (2000) Cloning and expression of the chicken immunoglobulin joining (J)-chain cDNA. Immunogenetics 51:85-91
Novak, J; Tomana, M; Kilian, M et al. (2000) Heterogeneity of O-glycosylation in the hinge region of human IgA1. Mol Immunol 37:1047-56
Julian, B A (2000) Treatment of IgA nephropathy. Semin Nephrol 20:277-85
Julian, B A; Tomana, M; Novak, J et al. (1999) Progress in the pathogenesis of IgA nephropathy. Adv Nephrol Necker Hosp 29:53-72
Tomana, M; Novak, J; Julian, B A et al. (1999) Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodies. J Clin Invest 104:73-81
Wyatt, R J; Julian, B A; Baehler, R W et al. (1998) Epidemiology of IgA nephropathy in central and eastern Kentucky for the period 1975 through 1994. Central Kentucky Region of the Southeastern United States IgA Nephropathy DATABANK Project. J Am Soc Nephrol 9:853-8
Tomana, M; Matousovic, K; Julian, B A et al. (1997) Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with IgG. Kidney Int 52:509-16

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