Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
1R01DK050015-01A1
Application #
2150991
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1996-05-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Boston Biomedical Research Institute
Department
Type
DUNS #
058893371
City
Watertown
State
MA
Country
United States
Zip Code
02472
Crossley, Lisa J (2003) Neutrophil activation by fMLP regulates FOXO (forkhead) transcription factors by multiple pathways, one of which includes the binding of FOXO to the survival factor Mcl-1. J Leukoc Biol 74:583-92
Zhan, Qian; Ge, Qingyuan; Ohira, Taisuke et al. (2003) p21-activated kinase 2 in neutrophils can be regulated by phosphorylation at multiple sites and by a variety of protein phosphatases. J Immunol 171:3785-93
Zhan, Qian; Bamburg, James R; Badwey, John A (2003) Products of phosphoinositide specific phospholipase C can trigger dephosphorylation of cofilin in chemoattractant stimulated neutrophils. Cell Motil Cytoskeleton 54:1-15
Oyaizu, Kosuke; Kantarci, Alpdogan; Maeda, Hiroshi et al. (2003) Identification of mRNAs for the various diacylglycerol kinase isoforms in neutrophils from patients with localized aggressive periodontitis. J Periodontal Res 38:488-95
Ohira, Taisuke; Zhan, Qian; Ge, Qingyuan et al. (2003) Protein phosphorylation in neutrophils monitored with phosphospecific antibodies. J Immunol Methods 281:79-94
Robinson, John M; Badwey, John A (2002) Rapid association of cytoskeletal remodeling proteins with the developing phagosomes of human neutrophils. Histochem Cell Biol 118:117-25
Lian, Jian P; Crossley, Lisa; Zhan, Qian et al. (2002) The P21-activated protein kinases (Paks) receive and integrate messages from a variety of signaling pathways. Adv Exp Med Biol 507:497-502
Lian, J P; Crossley, L; Zhan, Q et al. (2001) Antagonists of calcium fluxes and calmodulin block activation of the p21-activated protein kinases in neutrophils. J Immunol 166:2643-50
De Mesquita, D D; Zhan, Q; Crossley, L et al. (2001) p90-RSK and Akt may promote rapid phosphorylation/inactivation of glycogen synthase kinase 3 in chemoattractant-stimulated neutrophils. FEBS Lett 502:84-8
Lian, J P; Toker, A; Badwey, J A (2001) Phosphorylation of the activation loop of gamma p21-activated kinase (gamma-Pak) and related kinases (MSTs) in normal and stressed neutrophils. J Immunol 166:6349-57

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