Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK050052-07
Application #
6635047
Study Section
General Medicine A Subcommittee 2 (GMA)
Program Officer
May, Michael K
Project Start
1996-08-01
Project End
2005-01-31
Budget Start
2003-04-01
Budget End
2004-01-31
Support Year
7
Fiscal Year
2003
Total Cost
$201,825
Indirect Cost
Name
Medical College of Wisconsin
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
937639060
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Kalra, Seema; Seetharam, Shakuntla; Yammani, Raghunatha R et al. (2004) Rat transcobalamin: cloning and regulation of mRNA expression. J Physiol 556:623-35
Kalra, Seema; Li, Ning; Yammani, Raghunatha R et al. (2004) Cobalamin (vitamin B12) binding, phylogeny, and synteny of human transcobalamin. Arch Biochem Biophys 431:189-96
Yammani, R R; Seetharam, S; Dahms, N M et al. (2003) Transcobalamin II receptor interacts with megalin in the renal apical brush border membrane. J Membr Biol 193:57-66
Seetharam, Bellur; Yammani, Raghunatha R (2003) Cobalamin transport proteins and their cell-surface receptors. Expert Rev Mol Med 5:1-18
Vanamala, Sravan K; Seetharam, Shakuntla; Yammani, Raghunatha R et al. (2003) Human transcobalamin II receptor binds to Staphylococcus aureus protein A: implications as to its structure and function. Arch Biochem Biophys 411:204-14
Kalra, Seema; Li, Ning; Seetharam, Shakuntla et al. (2003) Function and stability of human transcobalamin II: role of intramolecular disulfide bonds C98-C291 and C147-C187. Am J Physiol Cell Physiol 285:C150-60
Bauer, Joseph A; Morrison, Bei H; Grane, Ronald W et al. (2002) Effects of interferon beta on transcobalamin II-receptor expression and antitumor activity of nitrosylcobalamin. J Natl Cancer Inst 94:1010-9
Seetharam, B; Li, N (2000) Transcobalamin II and its cell surface receptor. Vitam Horm 59:337-66
Seetharam, B; Bose, S; Li, N (1999) Cellular import of cobalamin (Vitamin B-12). J Nutr 129:1761-4
Seetharam, B (1999) Receptor-mediated endocytosis of cobalamin (vitamin B12). Annu Rev Nutr 19:173-95

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