Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK050053-02
Application #
2017013
Study Section
General Medicine A Subcommittee 2 (GMA)
Project Start
1995-09-18
Project End
1999-08-31
Budget Start
1996-09-11
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Barnes-Jewish Hospital
Department
Type
DUNS #
City
Saint Louis
State
MO
Country
United States
Zip Code
63110

  Publications

Zheng, Xinglong; Sadler, J Evan (2002) Mucin-like domain of enteropeptidase directs apical targeting in Madin-Darby canine kidney cells. J Biol Chem 277:6858-63
Bodo, I; Katsumi, A; Tuley, E A et al. (2001) Type 1 von Willebrand disease mutation Cys1149Arg causes intracellular retention and degradation of heterodimers: a possible general mechanism for dominant mutations of oligomeric proteins. Blood 98:2973-9
Lu, D; Futterer, K; Korolev, S et al. (1999) Crystal structure of enteropeptidase light chain complexed with an analog of the trypsinogen activation peptide. J Mol Biol 292:361-73
Zheng, X; Lu, D; Sadler, J E (1999) Apical sorting of bovine enteropeptidase does not involve detergent-resistant association with sphingolipid-cholesterol rafts. J Biol Chem 274:1596-605
Yuan, X; Zheng, X; Lu, D et al. (1998) Structure of murine enterokinase (enteropeptidase) and expression in small intestine during development. Am J Physiol 274:G342-9
Xue, J; Wu, Q; Westfield, L A et al. (1998) Incomplete embryonic lethality and fatal neonatal hemorrhage caused by prothrombin deficiency in mice. Proc Natl Acad Sci U S A 95:7603-7
Kokame, K; Zheng, X; Sadler, J E (1998) Activation of thrombin-activable fibrinolysis inhibitor requires epidermal growth factor-like domain 3 of thrombomodulin and is inhibited competitively by protein C. J Biol Chem 273:12135-9
Lu, D; Yuan, X; Zheng, X et al. (1997) Bovine proenteropeptidase is activated by trypsin, and the specificity of enteropeptidase depends on the heavy chain. J Biol Chem 272:31293-300