Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
1R01DK050124-01A1
Application #
2017023
Study Section
Bio-Organic and Natural Products Chemistry Study Section (BNP)
Project Start
1996-09-27
Project End
2000-08-31
Budget Start
1996-09-27
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Salk Institute for Biological Studies
Department
Type
DUNS #
005436803
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Grace, Christy Rani R; Cervini, Laura; Gulyas, Jozsef et al. (2007) Astressin-amide and astressin-acid are structurally different in dimethylsulfoxide. Biopolymers 87:196-205
Grace, Christy Rani R; Erchegyi, Judit; Koerber, Steven C et al. (2006) Novel sst2-selective somatostatin agonists. Three-dimensional consensus structure by NMR. J Med Chem 49:4487-96
Erchegyi, Judit; Waser, Beatrice; Schaer, Jean-Claude et al. (2003) Novel sst(4)-selective somatostatin (SRIF) agonists. 3. Analogues amenable to radiolabeling. J Med Chem 46:5597-605
Erchegyi, Judit; Penke, Botond; Simon, Lajos et al. (2003) Novel sst(4)-selective somatostatin (SRIF) agonists. 2. Analogues with beta-methyl-3-(2-naphthyl)alanine substitutions at position 8. J Med Chem 46:5587-96
Rivier, Jean; Erchegyi, Judit; Hoeger, Carl et al. (2003) Novel sst(4)-selective somatostatin (SRIF) agonists. 1. Lead identification using a betide scan. J Med Chem 46:5579-86
Reubi, Jean Claude (2003) Peptide receptors as molecular targets for cancer diagnosis and therapy. Endocr Rev 24:389-427
Grace, Christy Rani R; Koerber, Steven C; Erchegyi, Judit et al. (2003) Novel sst(4)-selective somatostatin (SRIF) agonists. 4. Three-dimensional consensus structure by NMR. J Med Chem 46:5606-18
Yunker, Warren K; Smith, Sean; Graves, Chad et al. (2003) Endogenous hypothalamic somatostatins differentially regulate growth hormone secretion from goldfish pituitary somatotropes in vitro. Endocrinology 144:4031-41
Rivier, J E; Hoeger, C; Erchegyi, J et al. (2001) Potent somatostatin undecapeptide agonists selective for somatostatin receptor 1 (sst1). J Med Chem 44:2238-46
Reubi, J C; Schaer, J C; Wenger, S et al. (2000) SST3-selective potent peptidic somatostatin receptor antagonists. Proc Natl Acad Sci U S A 97:13973-8

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