Glucose Toxicity in Skeletal Muscle

Mueckler, Mike M.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK050332-02
• Application #: 2151384
• Study Section: Special Emphasis Panel (ZRG4-NTN (06))
• Project Start: 1995-08-01
• Project End: 1999-07-31
• Budget Start: 1996-08-01
• Budget End: 1997-07-31
• Support Year: 2
• Fiscal Year: 1996

Institution

• Name: Washington University
• Department: Physiology
• Type: Schools of Medicine
• DUNS #: 062761671
• City: Saint Louis
• State: MO
• Country: United States
• Zip Code: 63130

Publications

Hresko, R C; Mueckler, M (2000) A novel 68-kDa adipocyte protein phosphorylated on tyrosine in response to insulin and osmotic shock. J Biol Chem 275:18114-20

Hansen, P A; Wang, W; Marshall, B A et al. (1998) Dissociation of GLUT4 translocation and insulin-stimulated glucose transport in transgenic mice overexpressing GLUT1 in skeletal muscle. J Biol Chem 273:18173-9

Hresko, R C; Heimberg, H; Chi, M M et al. (1998) Glucosamine-induced insulin resistance in 3T3-L1 adipocytes is caused by depletion of intracellular ATP. J Biol Chem 273:20658-68

Buse, M G; Robinson, K A; Marshall, B A et al. (1996) Differential effects of GLUT1 or GLUT4 overexpression on hexosamine biosynthesis by muscles of transgenic mice. J Biol Chem 271:23197-202

Wang, W; Hansen, P A; Marshall, B A et al. (1996) Insulin unmasks a COOH-terminal Glut4 epitope and increases glucose transport across T-tubules in skeletal muscle. J Cell Biol 135:415-30