Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK051348-02
Application #
2017262
Study Section
Special Emphasis Panel (SRC (28))
Project Start
1995-09-01
Project End
2000-08-31
Budget Start
1996-09-23
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Minnesota Twin Cities
Department
Genetics
Type
Schools of Arts and Sciences
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455

  Publications

Sinha, Akhouri A; Fernandes, Eduardo T; Ewing, Stephen L et al. (2013) Prediction of immune surveillance responsive metastatic prostate cancer in pelvic lymph node and emergence of surveillance unresponsive/resistant metastatic cells. Anticancer Res 33:3635-43
Sinha, Akhouri A; Quast, Barry J; Wilson, Michael J et al. (2002) Prediction of pelvic lymph node metastasis by the ratio of cathepsin B to stefin A in patients with prostate carcinoma. Cancer 94:3141-9
Sinha, A A; Quast, B J; Wilson, M J et al. (2001) Ratio of cathepsin B to stefin A identifies heterogeneity within Gleason histologic scores for human prostate cancer. Prostate 48:274-84
Sinha, A A; Jamuar, M P; Wilson, M J et al. (2001) Plasma membrane association of cathepsin B in human prostate cancer: biochemical and immunogold electron microscopic analysis. Prostate 49:172-84
Wilson, M J; Ruhland, A R; Quast, B J et al. (2000) Dipeptidylpeptidase IV activities are elevated in prostate cancers and adjacent benign hyperplastic glands. J Androl 21:220-6
Sinha, A A; Quast, B J; Korkowski, J C et al. (1999) The relationship of cathepsin B and stefin A mRNA localization identifies a potentially aggressive variant of human prostate cancer within a Gleason histologic score. Anticancer Res 19:2821-9
Sinha, A A; Quast, B J; Reddy, P K et al. (1999) Intravenous injection of an immunoconjugate (anti-PSA-IgG conjugated to 5-fluoro-2'-deoxyuridine) selectively inhibits cell proliferation and induces cell death in human prostate cancer cell tumors grown in nude mice. Anticancer Res 19:893-902
Sinha, A A; Quast, B J; Wilson, M J et al. (1998) Immunocytochemical localization of an immunoconjugate (antibody IgG against prostatic acid phosphatase conjugated to 5-fluoro-2'-deoxyuridine) in human prostate tumors. Anticancer Res 18:1385-92
Sinha, A A; Quast, B J; Wilson, M J et al. (1998) Codistribution of procathepsin B and mature cathepsin B forms in human prostate tumors detected by confocal and immunofluorescence microscopy. Anat Rec 252:281-9
Wilson, M J; Sinha, A A (1997) Human prostate tumor angiogenesis in nude mice: metalloprotease and plasminogen activator activities during tumor growth and neovascularization of subcutaneously injected matrigel impregnated with human prostate tumor cells. Anat Rec 249:63-73