Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
1R01DK051364-01
Application #
2152449
Study Section
Special Emphasis Panel (SRC (07))
Project Start
1996-05-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Urology
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Chai, T C; Andersson, K E; Tuttle, J B et al. (2000) Altered neural control of micturition in the aged F344 rat. Urol Res 28:348-54
Clemow, D B; Steers, W D; Tuttle, J B (2000) Stretch-activated signaling of nerve growth factor secretion in bladder and vascular smooth muscle cells from hypertensive and hyperactive rats. J Cell Physiol 183:289-300
Steers, W D; Clemow, D B; Persson, K et al. (1999) Observations from the spontaneously hypertensive rat. Insight into NGF regulation and noradrenergic hyper-innervation in the lower urinary tract. Adv Exp Med Biol 462:283-92;discussion 311-20
Chai, T C; Gemalmaz, H; Andersson, K E et al. (1999) Persistently increased voiding frequency despite relief of bladder outlet obstruction. J Urol 161:1689-93
Chuang, A T; Strauss, J D; Murphy, R A et al. (1998) Sildenafil, a type-5 CGMP phosphodiesterase inhibitor, specifically amplifies endogenous cGMP-dependent relaxation in rabbit corpus cavernosum smooth muscle in vitro. J Urol 160:257-61
Chai, T C; Gray, M L; Steers, W D (1998) The incidence of a positive ice water test in bladder outlet obstructed patients: evidence for bladder neural plasticity. J Urol 160:34-8
Clemow, D B; Spitsbergen, J M; McCarty, R et al. (1998) Arterial nerve growth factor (NGF) mRNA, protein, and vascular smooth muscle cell NGF secretion in hypertensive and hyperactive rats. Exp Cell Res 244:196-205
Clemow, D B; McCarty, R; Steers, W D et al. (1997) Efferent and afferent neuronal hypertrophy associated with micturition pathways in spontaneously hypertensive rats. Neurourol Urodyn 16:293-303
Chai, T C; Steers, W D (1997) Neurophysiology of micturition and continence in women. Int Urogynecol J Pelvic Floor Dysfunct 8:85-97