Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
1R01DK051809-01
Application #
2017438
Study Section
Special Emphasis Panel (SRC (06))
Project Start
1996-09-30
Project End
2000-08-31
Budget Start
1996-09-30
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Florida
Department
Pediatrics
Type
Schools of Medicine
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611

  Publications

Fischer, Anne C; Smith, Carolina I; Cebotaru, Liudmila et al. (2007) Expression of a truncated cystic fibrosis transmembrane conductance regulator with an AAV5-pseudotyped vector in primates. Mol Ther 15:756-63
Virella-Lowell, Isabel; Zusman, Benjamin; Foust, Kevin et al. (2005) Enhancing rAAV vector expression in the lung. J Gene Med 7:842-50
Flotte, Terence R; Schwiebert, Erik M; Zeitlin, Pamela L et al. (2005) Correlation between DNA transfer and cystic fibrosis airway epithelial cell correction after recombinant adeno-associated virus serotype 2 gene therapy. Hum Gene Ther 16:921-8
Flotte, Terence R; Zeitlin, Pamela L; Reynolds, Thomas C et al. (2003) Phase I trial of intranasal and endobronchial administration of a recombinant adeno-associated virus serotype 2 (rAAV2)-CFTR vector in adult cystic fibrosis patients: a two-part clinical study. Hum Gene Ther 14:1079-88
Fischer, Anne C; Beck, Suzanne E; Smith, Carolina I et al. (2003) Successful transgene expression with serial doses of aerosolized rAAV2 vectors in rhesus macaques. Mol Ther 8:918-26
Beck, Suzanne E; Laube, Beth L; Barberena, Carolina I et al. (2002) Deposition and expression of aerosolized rAAV vectors in the lungs of Rhesus macaques. Mol Ther 6:546-54
Seo, Byoung Boo; Nakamaru-Ogiso, Eiko; Flotte, Terence R et al. (2002) A single-subunit NADH-quinone oxidoreductase renders resistance to mammalian nerve cells against complex I inhibition. Mol Ther 6:336-41
Flotte, Terence R (2002) Recombinant adeno-associated virus gene therapy for cystic fibrosis and alpha(1)-antitrypsin deficiency. Chest 121:98S-102S
Flotte, T; Agarwal, A; Wang, J et al. (2001) Efficient ex vivo transduction of pancreatic islet cells with recombinant adeno-associated virus vectors. Diabetes 50:515-20
Song, S; Embury, J; Laipis, P J et al. (2001) Stable therapeutic serum levels of human alpha-1 antitrypsin (AAT) after portal vein injection of recombinant adeno-associated virus (rAAV) vectors. Gene Ther 8:1299-306

Showing the most recent 10 out of 20 publications