Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK052343-06
Application #
6684113
Study Section
General Medicine A Subcommittee 2 (GMA)
Program Officer
May, Michael K
Project Start
1998-01-01
Project End
2006-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
6
Fiscal Year
2004
Total Cost
$310,800
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Dusing, Mary R; Maier, Elizabeth A; Aronow, Bruce J et al. (2010) Onecut-2 knockout mice fail to thrive during early postnatal period and have altered patterns of gene expression in small intestine. Physiol Genomics 42:115-25
Maier, Elizabeth A; Dusing, Mary R; Wiginton, Dan A (2006) Temporal regulation of enhancer function in intestinal epithelium: a role for Onecut factors. J Biol Chem 281:32263-71
Dusing, Mary R; Wiginton, Dan A (2005) Epithelial lineages of the small intestine have unique patterns of GATA expression. J Mol Histol 36:15-24
Dusing, Mary R; Florence, Elizabeth A; Wiginton, Dan A (2003) High-level activation by a duodenum-specific enhancer requires functional GATA binding sites. Am J Physiol Gastrointest Liver Physiol 284:G1053-65
Bates, Michael D; Erwin, Christopher R; Sanford, L Philip et al. (2002) Novel genes and functional relationships in the adult mouse gastrointestinal tract identified by microarray analysis. Gastroenterology 122:1467-82
Dusing, M R; Florence, E A; Wiginton, D A (2001) Pdx-1 is required for activation in vivo from a duodenum-specific enhancer. J Biol Chem 276:14434-42
Dusing, M R; Brickner, A G; Lowe, S Y et al. (2000) A duodenum-specific enhancer regulates expression along three axes in the small intestine. Am J Physiol Gastrointest Liver Physiol 279:G1080-93