Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
3R01DK053069-04S1
Application #
6886409
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Rankin, Tracy L
Project Start
1999-05-01
Project End
2007-04-30
Budget Start
2003-05-01
Budget End
2004-04-30
Support Year
4
Fiscal Year
2004
Total Cost
$17,926
Indirect Cost
Name
La Biomed Research Institute/ Harbor UCLA Medical Center
Department
Type
DUNS #
069926962
City
Torrance
State
CA
Country
United States
Zip Code
90502
Ferrini, Monica G; Moon, Joanne; Rivera, Steve et al. (2012) Amelioration of diabetes-induced cavernosal fibrosis by antioxidant and anti-transforming growth factor-?1 therapies in inducible nitric oxide synthase-deficient mice. BJU Int 109:586-93
Toblli, Jorge E; Cao, Gabriel; Giani, Jorge F et al. (2011) Antifibrotic effects of pioglitazone at low doses on the diabetic rat kidney are associated with the improvement of markers of cell turnover, tubular and endothelial integrity, and angiogenesis. Kidney Blood Press Res 34:20-33
Gonzalez-Cadavid, Nestor F; Rajfer, Jacob (2010) Treatment of Peyronie's disease with PDE5 inhibitors: an antifibrotic strategy. Nat Rev Urol 7:215-21
Ferrini, Monica G; Rivera, Steve; Moon, Joanne et al. (2010) The genetic inactivation of inducible nitric oxide synthase (iNOS) intensifies fibrosis and oxidative stress in the penile corpora cavernosa in type 1 diabetes. J Sex Med 7:3033-44
Ferrini, Monica G; Kovanecz, Istvan; Sanchez, Sandra et al. (2009) Fibrosis and loss of smooth muscle in the corpora cavernosa precede corporal veno-occlusive dysfunction (CVOD) induced by experimental cavernosal nerve damage in the rat. J Sex Med 6:415-28
Gonzalez-Cadavid, Nestor F; Rajfer, Jacob (2009) Experimental models of Peyronie's disease. Implications for new therapies. J Sex Med 6:303-13
Kovanecz, Istvan; Nolazco, Gaby; Ferrini, Monica G et al. (2009) Early onset of fibrosis within the arterial media in a rat model of type 2 diabetes mellitus with erectile dysfunction. BJU Int 103:1396-404
Toblli, Jorge E; Ferrini, Monica G; Cao, Gabriel et al. (2009) Antifibrotic effects of pioglitazone on the kidney in a rat model of type 2 diabetes mellitus. Nephrol Dial Transplant 24:2384-91
Nolazco, Gaby; Kovanecz, Istvan; Vernet, Dolores et al. (2008) Effect of muscle-derived stem cells on the restoration of corpora cavernosa smooth muscle and erectile function in the aged rat. BJU Int 101:1156-64
Kovanecz, I; Rambhatla, A; Ferrini, M et al. (2008) Long-term continuous sildenafil treatment ameliorates corporal veno-occlusive dysfunction (CVOD) induced by cavernosal nerve resection in rats. Int J Impot Res 20:202-12

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