The overall objective of this study is to evaluate the effectiveness of brief counseling sessions for the management of obesity. The interventions are: Treatment A: orlistat + 12 monthly clinic visits (no cognitive behavior therapy [CBT]); Treatment B: 12 monthly brief individual CBT counseling sessions; Treatment C: orlistat + 12 monthly brief individual CBT counseling sessions. The proposed study will recruit and randomly assign 246 obese (BMI 30 to 40) adult women and men to the three conditions for one year.
Specific Aim 1 is to compare the effectiveness of the treatment groups as assessed by changes in BMI and weight.
Specific Aim 2 is to compare changes in other health outcomes (blood lipids, blood pressure and glucose). Secondary hypotheses will include examination of main effects and attendance, pill counts, dietary recall and exercise recall and maintenance of weight losses. The investigators believe that this study is significant because it will test a model for obesity treatment (brief individual CBT counseling) that can be applied expeditiously and conveniently to patients in a primary care setting.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
1R01DK058299-01A1
Application #
6332112
Study Section
Special Emphasis Panel (ZRG1-RPHB-2 (01))
Program Officer
Yanovski, Susan Z
Project Start
2001-05-01
Project End
2004-04-30
Budget Start
2001-05-01
Budget End
2002-04-30
Support Year
1
Fiscal Year
2001
Total Cost
$380,594
Indirect Cost
Name
Baylor College of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Foreyt, John P (2006) The role of lifestyle modification in dysmetabolic syndrome management. Nestle Nutr Workshop Ser Clin Perform Programme 11:197-205; discussion 205-6
Poston, W S C; Haddock, C K; Pinkston, M M et al. (2006) Evaluation of a primary care-oriented brief counselling intervention for obesity with and without orlistat. J Intern Med 260:388-98
Foreyt, John P (2005) Need for lifestyle intervention: how to begin. Am J Cardiol 96:11E-14E