Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK061400-02
Application #
6690049
Study Section
General Medicine B Study Section (GMB)
Program Officer
Meyers, Catherine M
Project Start
2003-01-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$293,040
Indirect Cost

  Institution

Name
University of Virginia
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
065391526
City
Charlottesville
State
VA
Country
United States
Zip Code
22904

  Publications

Abadir, Peter M; Periasamy, Ammasi; Carey, Robert M et al. (2006) Angiotensin II type 2 receptor-bradykinin B2 receptor functional heterodimerization. Hypertension 48:316-22
Siragy, Helmy M; Xue, Chun; Abadir, Peter et al. (2005) Angiotensin subtype-2 receptors inhibit renin biosynthesis and angiotensin II formation. Hypertension 45:133-7
Awad, Alaa S; Webb, Randy L; Carey, Robert M et al. (2005) Increased renal production of angiotensin II and thromboxane B2 in conscious diabetic rats. Am J Hypertens 18:544-8
Xue, Chun; Siragy, Helmy M (2005) Local renal aldosterone system and its regulation by salt, diabetes, and angiotensin II type 1 receptor. Hypertension 46:584-90
Awad, Alaa S; Webb, Randy L; Carey, Robert M et al. (2004) Renal nitric oxide production is decreased in diabetic rats and improved by AT1 receptor blockade. J Hypertens 22:1571-7
Siragy, Helmy M (2004) AT1 and AT2 receptor in the kidney: role in health and disease. Semin Nephrol 24:93-100
Kalantarinia, Kambiz; Awad, Alaa S; Siragy, Helmy M (2003) Urinary and renal interstitial concentrations of TNF-alpha increase prior to the rise in albuminuria in diabetic rats. Kidney Int 64:1208-13
Abadir, Peter M; Carey, Robert M; Siragy, Helmy M (2003) Angiotensin AT2 receptors directly stimulate renal nitric oxide in bradykinin B2-receptor-null mice. Hypertension 42:600-4