Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK061436-02
Application #
6689610
Study Section
Human Embryology and Development Subcommittee 1 (HED)
Program Officer
Sato, Sheryl M
Project Start
2003-01-01
Project End
2004-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$213,343
Indirect Cost

  Institution

Name
Louisiana State University Hsc New Orleans
Department
Pediatrics
Type
Schools of Medicine
DUNS #
782627814
City
New Orleans
State
LA
Country
United States
Zip Code
70112

  Publications

Zhang, Tao; Chen, Chiachen; Breslin, Mary B et al. (2014) Extra-nuclear activity of INSM1 transcription factor enhances insulin receptor signaling pathway and Nkx6.1 expression through RACK1 interaction. Cell Signal 26:740-7
Yusuf, Dimas; Butland, Stefanie L; Swanson, Magdalena I et al. (2012) The transcription factor encyclopedia. Genome Biol 13:R24
Zhang, Tao; Saunee, Nicolle A; Breslin, Mary B et al. (2012) Functional role of an islet transcription factor, INSM1/IA-1, on pancreatic acinar cell trans-differentiation. J Cell Physiol 227:2470-9
Cai, Chuan Qi; Zhang, Tao; Breslin, Mary B et al. (2011) Both polymorphic variable number of tandem repeats and autoimmune regulator modulate differential expression of insulin in human thymic epithelial cells. Diabetes 60:336-44
Zhang, Tao; Wang, Hongwei; Saunee, Nicolle A et al. (2010) Insulinoma-associated antigen-1 zinc-finger transcription factor promotes pancreatic duct cell trans-differentiation. Endocrinology 151:2030-9
Wang, Hong-Wei; Breslin, Mary B; Chen, Chiachen et al. (2009) INSM1 promoter-driven adenoviral herpes simplex virus thymidine kinase cancer gene therapy for the treatment of primitive neuroectodermal tumors. Hum Gene Ther 20:1308-18
Zhang, Tao; Liu, Wei-Dong; Saunee, Nicolle A et al. (2009) Zinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrest. J Biol Chem 284:5574-81
Lan, Michael S; Breslin, Mary B (2009) Structure, expression, and biological function of INSM1 transcription factor in neuroendocrine differentiation. FASEB J 23:2024-33
Wang, Hong-Wei; Muguira, Michelle; Liu, Wei-Dong et al. (2008) Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription. J Endocrinol 198:29-39
Breslin, Mary B; Wang, Hong-Wei; Pierce, Amy et al. (2007) Neurogenin 3 recruits CBP co-activator to facilitate histone H3/H4 acetylation in the target gene INSM1. FEBS Lett 581:949-54

Showing the most recent 10 out of 15 publications