Hormonal Control of Histone Modifications in ES Cells

Fritsch, Michael K.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Research Project (R01)
• Project #: 5R01DK064243-02
• Application #: 6704228
• Study Section: Biochemical Endocrinology Study Section (BCE)
• Program Officer: Margolis, Ronald N
• Project Start: 2003-03-01
• Project End: 2008-01-31
• Budget Start: 2004-02-01
• Budget End: 2005-01-31
• Support Year: 2
• Fiscal Year: 2004
• Total Cost: $285,747

Institution

• Name: University of Wisconsin Madison
• Department: Pathology
• Type: Schools of Medicine
• DUNS #: 161202122
• City: Madison
• State: WI
• Country: United States
• Zip Code: 53715

Publications

Oduro, Akua K; Fritsch, Michael K; Murdoch, Fern E (2008) Chromatin context dominates estrogen regulation of pS2 gene expression. Exp Cell Res 314:2796-810

McCool, Kevin W; Xu, Xiaojie; Singer, Don B et al. (2007) The role of histone acetylation in regulating early gene expression patterns during early embryonic stem cell differentiation. J Biol Chem 282:6696-706

Lee, Elliot R; Murdoch, Fern E; Fritsch, Michael K (2007) High histone acetylation and decreased polycomb repressive complex 2 member levels regulate gene specific transcriptional changes during early embryonic stem cell differentiation induced by retinoic acid. Stem Cells 25:2191-9

Lee, Elliot R; McCool, Kevin W; Murdoch, Fern E et al. (2006) Dynamic changes in histone H3 phosphoacetylation during early embryonic stem cell differentiation are directly mediated by mitogen- and stress-activated protein kinase 1 via activation of MAPK pathways. J Biol Chem 281:21162-72

Sauter, Carley N; McDermid, Rebecca L; Weinberg, Amy L et al. (2005) Differentiation of murine embryonic stem cells induces progesterone receptor gene expression. Exp Cell Res 311:251-64