The prevalence of obesity continues to rise, and the striking increases in childhood obesity over the past several decades are particularly alarming. Recent data suggest that 31 percent of children in the U.S. are either overweight or obese and these children at a greater risk for adult obesity and negative health and psychosocial consequences in childhood and adulthood. Although 1/3 of children who participate in family-based obesity treatment decreased their percentage overweight 10 years later, 2/3 of the children continue to struggle with their weight. One potential opportunity for improving childhood obesity treatment is to intervene with the parents, without child involvement. Parent-only interventions are potentially promising for a number of reasons, including decreased treatment costs, developmental appropriateness for the child, promising data, and improved generalizability. This project will fill this gap in the literature, by completing the following primary and secondary aims. Primary aim 1: To evaluate the effectiveness of a behavioral parent-only intervention for childhood obesity on the target child's weight compared to the parent + child group. We hypothesize that the parent-only treatment will produce child weight loss (BMI_Z, BMI-P) that is not inferior to the parent + child treatment group immediately following treatment and at 6-, 12- months and 18- months post-treatment. Primary aim 2: To evaluate the cost effectiveness of a parent-only group, as compared to the parent + child group. We hypothesize that the parent-only group will be more cost-effective than the parent + child group, as measured by calculating cost effectiveness ratios from both third party payer and limited societal perspectives. As secondary aims, we will 1) Compare effect of the treatment groups on child and parent diet and exercise behavior, quality of life, psychosocial measures, parenting skills and 2) Evaluate predictors of success for child weight loss, including group attendance, adherence to behavioral recommendations, household environment, parenting style, parent and child psychosocial functioning, and parent weight loss at 6-, 12- and 18- months post-treatment.
Aims will be achieved through a randomized clinical trial in which 150 overweight 8-12 year old children and at least one of their overweight parents will be randomly assigned by the gender of the child to one of two conditions;Parent-only intervention or Parent + child intervention. Both treatment arms will provide behavioral treatment for childhood obesity for 5 months. Assessments include baseline, immediately post-treatment, and 6-, 12- and 18-months post-treatment. Results of these studies will be utilized as data to recommend changes in the standard treatment for childhood obesity. This program of research is critical for exploring and developing interventions mobilizing parents to treat and prevent childhood obesity.

Public Health Relevance

Narrative This project aims to evaluate the effectiveness of a parent-only treatment for childhood obesity compared to the standard treatment of parent + child. Information from this study may lead to lower-cost treatment alternatives with equivalent outcomes, findings that would contribute to significant and meaningful changes in the approach to treatment of childhood obesity.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK075861-03
Application #
8293277
Study Section
Psychosocial Risk and Disease Prevention Study Section (PRDP)
Program Officer
Horlick, Mary
Project Start
2010-07-01
Project End
2015-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
3
Fiscal Year
2012
Total Cost
$622,459
Indirect Cost
$219,573
Name
University of California San Diego
Department
Pediatrics
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
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Mestre, Z L; Bischoff-Grethe, A; Eichen, D M et al. (2017) Hippocampal atrophy and altered brain responses to pleasant tastes among obese compared with healthy weight children. Int J Obes (Lond) 41:1496-1502
Liang, June; Matheson, Brittany E; Rhee, Kyung E et al. (2016) Parental control and overconsumption of snack foods in overweight and obese children. Appetite 100:181-8
Boutelle, Kerri N; Braden, Abby; Douglas, Jennifer M et al. (2015) Design of the FRESH study: A randomized controlled trial of a parent-only and parent-child family-based treatment for childhood obesity. Contemp Clin Trials 45:364-370
Braden, Abby; Strong, David; Crow, Scott et al. (2015) Parent changes in diet, physical activity, and behavior in family-based treatment for childhood obesity. Clin Pediatr (Phila) 54:494-7
Boutelle, K N; Wierenga, C E; Bischoff-Grethe, A et al. (2015) Increased brain response to appetitive tastes in the insula and amygdala in obese compared with healthy weight children when sated. Int J Obes (Lond) 39:620-8
Boutelle, Kerri N; Bouton, Mark E (2015) Implications of learning theory for developing programs to decrease overeating. Appetite 93:62-74
Liang, J; Matheson, B E; Kaye, W H et al. (2014) Neurocognitive correlates of obesity and obesity-related behaviors in children and adolescents. Int J Obes (Lond) 38:494-506
Feldstein, Ariel E; Patton-Ku, Dana; Boutelle, Kerri N (2014) Obesity, nutrition, and liver disease in children. Clin Liver Dis 18:219-31
Rhee, Kyung E; Pan, Teresa Y; Norman, Gregory J et al. (2013) Relationship between maternal parenting and eating self-efficacy in overweight children when stressed. Eat Weight Disord 18:283-8

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