Abstract

The overall goal of this proposal is to develop the new RF coil technology and physical understanding required to safely achieve the performance advantages inherent to high field NMR for biomedical research and diagnostics. Because the University of Minnesota and its Center for Magnetic Resonance Research are unique with their complement of 4T, 7T and 9.4T whole body magnet platforms, an unprecedented opportunity is now afforded to develop a continuum of engineering solutions and physical data for the upper spectrum of high field systems and applications. This goal continues from the original grant's aims to advance human head and brain imaging to 7T. With the original aims largely met, the objective of the present proposal for continuation expands on the original research in three ways. 1.) New theoretical models will be developed for RF propagation and loss to 400 MHz (9.4T). 2.) Based on these model results, new approaches will be developed for RF parameter optimization at the highest fields. 3.) These innovative RF optimization approaches will be realized in innovative new technologies for body imaging to 7T and for head imaging to 9.4T.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Research Project (R01)
Project #
5R01EB000895-05
Application #
6945137
Study Section
Biomedical Imaging Technology Study Section (BMIT)
Program Officer
Mclaughlin, Alan Charles
Project Start
2002-12-01
Project End
2008-07-31
Budget Start
2005-08-01
Budget End
2006-07-31
Support Year
5
Fiscal Year
2005
Total Cost
$344,065
Indirect Cost

  Institution

Name
University of Minnesota Twin Cities
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455

  Publications

Akgun, Can E; DelaBarre, Lance; Yoo, Hyoungsuk et al. (2014) Stepped impedance resonators for high-field magnetic resonance imaging. IEEE Trans Biomed Eng 61:327-33
Sohn, Sung-Min; DelaBarre, Lance; Gopinath, Anand et al. (2014) RF Head Coil Design with Improved RF Magnetic Near-Fields Uniformity for Magnetic Resonance Imaging (MRI) Systems. IEEE Trans Microw Theory Tech 62:1784-1789
Shrivastava, Devashish; Utecht, Lynn; Tian, Jinfeng et al. (2014) In vivo radiofrequency heating in swine in a 3T (123.2-MHz) birdcage whole body coil. Magn Reson Med 72:1141-50
Metzger, Gregory J; Auerbach, Edward J; Akgun, Can et al. (2013) Dynamically applied B1+ shimming solutions for non-contrast enhanced renal angiography at 7.0 Tesla. Magn Reson Med 69:114-26
Liu, Wanzhan; Kao, Chien-ping; Collins, Christopher M et al. (2013) On consideration of radiated power in RF field simulations for MRI. Magn Reson Med 69:290-4
Suttie, J J; Delabarre, L; Pitcher, A et al. (2012) 7 Tesla (T) human cardiovascular magnetic resonance imaging using FLASH and SSFP to assess cardiac function: validation against 1.5 T and 3 T. NMR Biomed 25:27-34
Snyder, C J; Delabarre, L; Moeller, S et al. (2012) Comparison between eight- and sixteen-channel TEM transceive arrays for body imaging at 7 T. Magn Reson Med 67:954-64
Shrivastava, Devashish; Hanson, Timothy; Kulesa, Jeramy et al. (2011) Radiofrequency heating in porcine models with a ""large"" 32 cm internal diameter, 7 T (296 MHz) head coil. Magn Reson Med 66:255-63
Adriany, Gregor; Auerbach, Edward J; Snyder, Carl J et al. (2010) A 32-channel lattice transmission line array for parallel transmit and receive MRI at 7 tesla. Magn Reson Med 63:1478-85
Oh, Sukhoon; Webb, Andrew G; Neuberger, Thomas et al. (2010) Experimental and numerical assessment of MRI-induced temperature change and SAR distributions in phantoms and in vivo. Magn Reson Med 63:218-23

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