Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Research Project (R01)
Project #
8R01EB002047-02
Application #
6623304
Study Section
Surgery and Bioengineering Study Section (SB)
Program Officer
Moy, Peter
Project Start
2002-04-01
Project End
2006-03-31
Budget Start
2003-04-01
Budget End
2004-03-31
Support Year
2
Fiscal Year
2003
Total Cost
$346,301
Indirect Cost
Name
University of California San Francisco
Department
Pharmacology
Type
Schools of Pharmacy
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Kierstead, Paul H; Okochi, Hideaki; Venditto, Vincent J et al. (2015) The effect of polymer backbone chemistry on the induction of the accelerated blood clearance in polymer modified liposomes. J Control Release 213:1-9
Kohli, Aditya G; Kierstead, Paul H; Venditto, Vincent J et al. (2014) Designer lipids for drug delivery: from heads to tails. J Control Release 190:274-87
Kieler-Ferguson, Heidi M; Frechet, Jean M J; Szoka Jr, Francis C (2013) Clinical developments of chemotherapeutic nanomedicines: polymers and liposomes for delivery of camptothecins and platinum (II) drugs. Wiley Interdiscip Rev Nanomed Nanobiotechnol 5:130-8
Klemm, Piper J; Floyd 3rd, William C; Smiles, Danil E et al. (2012) Improving T? and T? magnetic resonance imaging contrast agents through the conjugation of an esteramide dendrimer to high-water-coordination Gd(III) hydroxypyridinone complexes. Contrast Media Mol Imaging 7:95-9
Chen, Bo; van der Poll, Derek G; Jerger, Katherine et al. (2011) Synthesis and properties of star-comb polymers and their doxorubicin conjugates. Bioconjug Chem 22:617-24
Floyd 3rd, William C; Datta, Gopal K; Imamura, Shinichi et al. (2011) Chemotherapeutic evaluation of a synthetic tubulysin analogue-dendrimer conjugate in c26 tumor bearing mice. ChemMedChem 6:49-53
Floyd 3rd, William C; Klemm, Piper J; Smiles, Danil E et al. (2011) Conjugation effects of various linkers on Gd(III) MRI contrast agents with dendrimers: optimizing the hydroxypyridinonate (HOPO) ligands with nontoxic, degradable esteramide (EA) dendrimers for high relaxivity. J Am Chem Soc 133:2390-3
van der Poll, Derek G; Kieler-Ferguson, Heidi M; Floyd, William C et al. (2010) Design, synthesis, and biological evaluation of a robust, biodegradable dendrimer. Bioconjug Chem 21:764-73
Fox, Megan E; Guillaudeu, Steve; Fréchet, Jean M J et al. (2009) Synthesis and in vivo antitumor efficacy of PEGylated poly(l-lysine) dendrimer-camptothecin conjugates. Mol Pharm 6:1562-72
Chen, Bo; Jerger, Katherine; Fréchet, Jean M J et al. (2009) The influence of polymer topology on pharmacokinetics: differences between cyclic and linear PEGylated poly(acrylic acid) comb polymers. J Control Release 140:203-9

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