Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES002866-09
Application #
3250114
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1981-09-15
Project End
1993-06-30
Budget Start
1993-01-01
Budget End
1993-06-30
Support Year
9
Fiscal Year
1993
Total Cost
Indirect Cost

  Institution

Name
University of Minnesota Twin Cities
Department
Type
Schools of Public Health
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455

  Publications

Lorick, K L; Toscano, D L; Toscano Jr, W A (1998) 2,3,7,8-Tetrachlorodibenzo-p-dioxin alters retinoic acid receptor function in human keratinocytes. Biochem Biophys Res Commun 243:749-52
McNulty, S E; Toscano Jr, W A (1995) Transcriptional regulation of glyceraldehyde-3-phosphate dehydrogenase by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochem Biophys Res Commun 212:165-71
Choi, E J; Toscano, D G; Ryan, J A et al. (1991) Dioxin induces transforming growth factor-alpha in human keratinocytes. J Biol Chem 266:9591-7
Su, L N; Toscano Jr, W A; Kennedy, A R (1991) Suppression of phorbol ester-enhanced radiation-induced malignancy in vitro by protease inhibitors is independent of protein kinase C. Biochem Biophys Res Commun 176:18-24
Wiencke, J K; Kelsey, K T; Lamela, R A et al. (1990) Genetic polymorphisms in carcinogen metabolism predict substrate-induced cytogenetic damage in humans. Prog Clin Biol Res 340B:137-47
Greenlee, W F; Osborne, R; Dold, K M et al. (1985) Toxicity of chlorinated aromatic compounds in animals and humans: in vitro approaches to toxic mechanisms and risk assessment. Environ Health Perspect 60:69-76
Hudson, L G; Toscano Jr, W A; Greenlee, W F (1985) Regulation of epidermal growth factor binding in a human keratinocyte cell line by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Appl Pharmacol 77:251-9