Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
2R01ES003127-15
Application #
2153230
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1982-07-01
Project End
2001-04-30
Budget Start
1996-05-28
Budget End
1997-04-30
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Rochester
Department
Pharmacology
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627

  Publications

Board, Philip G; Anders, M W (2007) Glutathione transferase omega 1 catalyzes the reduction of S-(phenacyl)glutathiones to acetophenones. Chem Res Toxicol 20:149-54
Blackburn, Anneke C; Matthaei, Klaus I; Lim, Cindy et al. (2006) Deficiency of glutathione transferase zeta causes oxidative stress and activation of antioxidant response pathways. Mol Pharmacol 69:650-7
Anders, M W (2005) Formation and toxicity of anesthetic degradation products. Annu Rev Pharmacol Toxicol 45:147-76
Lim, Cindy E L; Matthaei, Klaus I; Blackburn, Anneke C et al. (2004) Mice deficient in glutathione transferase zeta/maleylacetoacetate isomerase exhibit a range of pathological changes and elevated expression of alpha, mu, and pi class glutathione transferases. Am J Pathol 165:679-93
Lantum, Hoffman B M; Iyer, Ramaswamy A; Anders, M W (2004) Acivicin-induced alterations in renal and hepatic glutathione concentrations and in gamma-glutamyltransferase activities. Biochem Pharmacol 67:1421-6
Anderson, Wayne B; Board, Philip G; Anders, M W (2004) Glutathione transferase zeta-catalyzed bioactivation of dichloroacetic acid: reaction of glyoxylate with amino acid nucleophiles. Chem Res Toxicol 17:650-62
Lantum, Hoffman B M; Cornejo, Judith; Pierce, Robert H et al. (2003) Perturbation of maleylacetoacetic acid metabolism in rats with dichloroacetic Acid-induced glutathione transferase zeta deficiency. Toxicol Sci 74:192-202
Jolivette, Larry J; Anders, M W (2003) Computational and experimental studies on the distribution of addition and substitution products of the microsomal glutathione transferase 1-catalyzed conjugation of glutathione with fluoroalkenes. Chem Res Toxicol 16:137-44
Board, Philip G; Taylor, Matthew C; Coggan, Marjorie et al. (2003) Clarification of the role of key active site residues of glutathione transferase zeta/maleylacetoacetate isomerase by a new spectrophotometric technique. Biochem J 374:731-7
Lantum, Hoffman B M; Baggs, Raymond B; Krenitsky, Daria M et al. (2002) Nephrotoxicity of chlorofluoroacetic acid in rats. Toxicol Sci 70:261-8

Showing the most recent 10 out of 113 publications