Mercury Induced Autoimmune Disease

Bigazzi, Pierluigi E.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Environmental Health Sciences (NIEHS)
• Type: Research Project (R01)
• Project #: 5R01ES003230-08
• Application #: 2153263
• Study Section: Toxicology Subcommittee 2 (TOX)
• Project Start: 1983-08-01
• Project End: 1998-03-31
• Budget Start: 1996-04-01
• Budget End: 1997-03-31
• Support Year: 8
• Fiscal Year: 1996

Institution

• Name: University of Connecticut
• Department: Pathology
• Type: Schools of Dentistry
• City: Farmington
• State: CT
• Country: United States
• Zip Code: 06030

Publications

Bigazzi, P E; Kosuda, L L; Hannigan, M O et al. (2003) Lack of graft-versus-host-like pathology in mercury-induced autoimmunity of Brown Norway rats. Clin Immunol 109:229-37

Bigazzi, P E (1999) Metals and kidney autoimmunity. Environ Health Perspect 107 Suppl 5:753-65

Bigazzi, P E (1997) Autoimmunity caused by xenobiotics. Toxicology 119:1-21

Kosuda, L L; Hannigan, M O; Bigazzi, P E et al. (1996) Thymus atrophy and changes in thymocyte subpopulations of BN rats with mercury-induced renal autoimmune disease. Autoimmunity 23:77-89

Kosuda, L L; Greiner, D L; Bigazzi, P E (1994) Mercury-induced renal autoimmunity in BN-->LEW.1N chimeric rats. Cell Immunol 155:77-94

Kosuda, L L; Hosseinzadeh, H; Greiner, D L et al. (1994) Role of RT6+ T lymphocytes in mercury-induced renal autoimmunity: experimental manipulations of ""susceptible"" and ""resistant"" rats. J Toxicol Environ Health 42:303-21

Bigazzi, P E (1994) Autoimmunity and heavy metals. Lupus 3:449-53

Kosuda, L L; Greiner, D L; Bigazzi, P E (1993) Mercury-induced renal autoimmunity: changes in RT6+ T-lymphocytes of susceptible and resistant rats. Environ Health Perspect 101:178-85

Contrino, J; Kosuda, L L; Marucha, P et al. (1992) The in vitro effects of mercury on peritoneal leukocytes (PMN and macrophages) from inbred brown Norway and Lewis rats. Int J Immunopharmacol 14:1051-9

Potter, N T; Bigazzi, P E (1992) Acute optic neuritis associated with immunization with the CNS myelin proteolipid protein. Invest Ophthalmol Vis Sci 33:1717-22