NMR Studies of Metallothionein Structure and Reactivity

Otvos, James D.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Environmental Health Sciences (NIEHS)
• Type: Research Project (R01)
• Project #: 5R01ES004036-05
• Application #: 3251872
• Study Section: Metallobiochemistry Study Section (BMT)
• Project Start: 1986-04-01
• Project End: 1990-07-22
• Budget Start: 1990-04-01
• Budget End: 1990-07-22
• Support Year: 5
• Fiscal Year: 1990

Institution

• Name: University of Wisconsin Milwaukee
• Type: Schools of Arts and Sciences
• City: Milwaukee
• State: WI
• Country: United States
• Zip Code: 53201

Publications

Li, H; Otvos, J D (1998) Biphasic kinetics of Zn2+ removal from Zn metallothionein by nitrilotriacetate are associated with differential reactivity of the two metal clusters. J Inorg Biochem 70:187-94

Li, H; Otvos, J D (1996) 111Cd NMR studies of the domain specificity of Ag+ and Cu+ binding to metallothionein. Biochemistry 35:13929-36

Li, H; Otvos, J D (1996) HPLC characterization of Ag+ and Cu+ metal exchange reactions with Zn- and Cd-metallothioneins. Biochemistry 35:13937-45