Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
3R01ES005495-03S1
Application #
2154123
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1992-07-01
Project End
1997-06-30
Budget Start
1994-07-01
Budget End
1995-06-30
Support Year
3
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of New Mexico
Department
Type
Schools of Pharmacy
DUNS #
829868723
City
Albuquerque
State
NM
Country
United States
Zip Code
87131
Li, Qian; Lauer, Fredine T; Liu, Ke Jian et al. (2010) Low-dose synergistic immunosuppression of T-dependent antibody responses by polycyclic aromatic hydrocarbons and arsenic in C57BL/6J murine spleen cells. Toxicol Appl Pharmacol 245:344-51
Mitchell, L A; Lauer, F T; Burchiel, S W et al. (2009) Mechanisms for how inhaled multiwalled carbon nanotubes suppress systemic immune function in mice. Nat Nanotechnol 4:451-6
Gao, Jun; Mitchell, Leah A; Lauer, Fredine T et al. (2008) p53 and ATM/ATR regulate 7,12-dimethylbenz[a]anthracene-induced immunosuppression. Mol Pharmacol 73:137-46
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Burchiel, Scott W; Lauer, Fredine T; Dunaway, Sandy L et al. (2005) Hardwood smoke alters murine splenic T cell responses to mitogens following a 6-month whole body inhalation exposure. Toxicol Appl Pharmacol 202:229-36
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Burchiel, Scott W; Lauer, Fredine T; McDonald, Jacob D et al. (2004) Systemic immunotoxicity in AJ mice following 6-month whole body inhalation exposure to diesel exhaust. Toxicol Appl Pharmacol 196:337-45
Kepley, Christopher L; Lauer, Fredine T; Oliver, Janet M et al. (2003) Environmental polycyclic aromatic hydrocarbons, benzo(a) pyrene (BaP) and BaP-quinones, enhance IgE-mediated histamine release and IL-4 production in human basophils. Clin Immunol 107:10-9
Reed, Matthew; Monske, Michael; Lauer, Fredine et al. (2003) Benzo[a]pyrene diones are produced by photochemical and enzymatic oxidation and induce concentration-dependent decreases in the proliferative state of human pulmonary epithelial cells. J Toxicol Environ Health A 66:1189-205
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