Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES005670-05
Application #
2154432
Study Section
Pathology A Study Section (PTHA)
Project Start
1991-04-01
Project End
1997-03-31
Budget Start
1995-04-01
Budget End
1997-03-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Adirondack Biomedical Research Institute
Department
Type
DUNS #
City
Lake Placid
State
NY
Country
United States
Zip Code
12946
Dong, L; Stevens, J L; Fabbro, D et al. (1994) Protein kinase C isozyme expression and down-modulation in growing, quiescent, and transformed renal proximal tubule epithelial cells. Cell Growth Differ 5:881-90
Yu, K; Chen, Q; Liu, H et al. (1994) Signalling the molecular stress response to nephrotoxic and mutagenic cysteine conjugates: differential roles for protein synthesis and calcium in the induction of c-fos and c-myc mRNA in LLC-PK1 cells. J Cell Physiol 161:303-11
Chapline, C; Ramsay, K; Klauck, T et al. (1993) Interaction cloning of protein kinase C substrates. J Biol Chem 268:6858-61
Zhang, G; Ichimura, T; Maier, J A et al. (1993) A role for fibroblast growth factor type-1 in nephrogenic repair. Autocrine expression in rat kidney proximal tubule epithelial cells in vitro and in the regenerating epithelium following nephrotoxic damage by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine in vi J Biol Chem 268:11542-7
Dong, L; Stevens, J L; Fabbro, D et al. (1993) Regulation of protein kinase C isozymes in kidney regeneration. Cancer Res 53:4542-9
Dong, L; Stevens, J L; Jaken, S (1993) Transformation-sensitive localization of alpha-protein kinase C at cell-cell contacts in rat renal proximal tubule epithelial cells. Cell Growth Differ 4:793-8
Ward, J M; Stevens, J L; Konishi, N et al. (1992) Vimentin metaplasia in renal cortical tubules of preneoplastic, neoplastic, aging, and regenerative lesions of rats and humans. Am J Pathol 141:955-64
Chen, Q; Yu, K; Holbrook, N J et al. (1992) Activation of the growth arrest and DNA damage-inducible gene gadd 153 by nephrotoxic cysteine conjugates and dithiothreitol. J Biol Chem 267:8207-12
Zhang, G H; Ichimura, T; Wallin, A et al. (1991) Regulation of rat proximal tubule epithelial cell growth by fibroblast growth factors, insulin-like growth factor-1 and transforming growth factor-beta, and analysis of fibroblast growth factors in rat kidney. J Cell Physiol 148:295-305
Dong, L Q; Stevens, J L; Jaken, S (1991) Biochemical and immunological characterization of renal protein kinase C. Am J Physiol 261:F679-87