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Bolton, J L; Pisha, E; Shen, L et al. (1997) The reactivity of o-quinones which do not isomerize to quinone methides correlates with alkylcatechol-induced toxicity in human melanoma cells. Chem Biol Interact 106:133-48
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Krol, E S; Bolton, J L (1997) Oxidation of 4-alkylphenols and catechols by tyrosinase: ortho-substituents alter the mechanism of quinoid formation. Chem Biol Interact 104:11-27
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Bolton, J L; Turnipseed, S B; Thompson, J A (1997) Influence of quinone methide reactivity on the alkylation of thiol and amino groups in proteins: studies utilizing amino acid and peptide models. Chem Biol Interact 107:185-200
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Shen, L; Pisha, E; Huang, Z et al. (1997) Bioreductive activation of catechol estrogen-ortho-quinones: aromatization of the B ring in 4-hydroxyequilenin markedly alters quinoid formation and reactivity. Carcinogenesis 18:1093-101
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Lewis, M A; Yoerg, D G; Bolton, J L et al. (1996) Alkylation of 2'-deoxynucleosides and DNA by quinone methides derived from 2,6-di-tert-butyl-4-methylphenol. Chem Res Toxicol 9:1368-74
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Bolton, J L; Shen, L (1996) p-Quinone methides are the major decomposition products of catechol estrogen o-quinones. Carcinogenesis 17:925-9
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Bolton, J L; Wu, H M; Hu, L Q (1996) Mechanism of isomerization of 4-propyl-o-quinone to its tautomeric p-quinone methide. Chem Res Toxicol 9:109-113
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Iverson, S L; Shen, L; Anlar, N et al. (1996) Bioactivation of estrone and its catechol metabolites to quinoid-glutathione conjugates in rat liver microsomes. Chem Res Toxicol 9:492-9
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Thompson, D C; Perera, K; Krol, E S et al. (1995) o-Methoxy-4-alkylphenols that form quinone methides of intermediate reactivity are the most toxic in rat liver slices. Chem Res Toxicol 8:323-7
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Bolton, J L; Comeau, E; Vukomanovic, V (1995) The influence of 4-alkyl substituents on the formation and reactivity of 2-methoxy-quinone methides: evidence that extended pi-conjugation dramatically stabilizes the quinone methide formed from eugenol. Chem Biol Interact 95:279-90
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