Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES006253-03
Application #
2155104
Study Section
Toxicology Subcommittee 2 (TOX)
Project Start
1993-08-01
Project End
1997-01-31
Budget Start
1995-08-01
Budget End
1997-01-31
Support Year
3
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Other Basic Sciences
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Gilbert, M E; Lasley, S M (2007) Developmental lead (Pb) exposure reduces the ability of the NMDA antagonist MK-801 to suppress long-term potentiation (LTP) in the rat dentate gyrus, in vivo. Neurotoxicol Teratol 29:385-93
Lasley, S M; Gilbert, M E (2002) Rat hippocampal glutamate and GABA release exhibit biphasic effects as a function of chronic lead exposure level. Toxicol Sci 66:139-47
Gilbert, M E; Mack, C M (1999) Field potential recordings in dentate gyrus of anesthetized rats: stability of baseline. Hippocampus 9:277-87
Lasley, S M; Green, M C; Gilbert, M E (1999) Influence of exposure period on in vivo hippocampal glutamate and GABA release in rats chronically exposed to lead. Neurotoxicology 20:619-29
Lasley, S M; Gilbert, M E (1999) Lead inhibits the rat N-methyl-d-aspartate receptor channel by binding to a site distinct from the zinc allosteric site. Toxicol Appl Pharmacol 159:224-33
Gilbert, M E; Mack, C M; Lasley, S M (1999) Chronic developmental lead exposure and hippocampal long-term potentiation: biphasic dose-response relationship. Neurotoxicology 20:71-82
Gilbert, M E; Mack, C M; Lasley, S M (1999) The influence of developmental period of lead exposure on long-term potentiation in the adult rat dentate gyrus in vivo. Neurotoxicology 20:57-69
Gilbert, M E; Liang, D (1998) Alterations in synaptic transmission and plasticity in hippocampus by a complex PCB mixture, Aroclor 1254. Neurotoxicol Teratol 20:383-9
Gilbert, M E; Mack, C M (1998) Chronic lead exposure accelerates decay of long-term potentiation in rat dentate gyrus in vivo. Brain Res 789:139-49
Lasley, S M; Gilbert, M E (1996) Presynaptic glutamatergic function in dentate gyrus in vivo is diminished by chronic exposure to inorganic lead. Brain Res 736:125-34

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