Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
2R01ES006365-04
Application #
2155231
Study Section
Special Emphasis Panel (ZRG4-ALTX-1 (01))
Project Start
1993-04-01
Project End
2000-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Zhou, M; Tian, X; Suszkiw, J B (2000) Developmental stage-dependent protective effect of NGF against lead cholinotoxicity in the rat septum. Brain Res 866:268-73
Tian, X; Sun, X; Suszkiw, J B (2000) Upregulation of tyrosine hydroxylase and downregulation of choline acetyltransferase in lead-exposed PC12 cells: the role of PKC activation. Toxicol Appl Pharmacol 167:246-52
Sun, X; Tian, X; Suszkiw, J B (1997) Reduction of vesicular acetylcholine transporter mRNA in the rat septum following lead exposure. Neuroreport 8:891-4
Sun, X; Tian, X; Suszkiw, J B (1997) Reduction of choline acetyltransferase mRNA in the septum of developing rat exposed to inorganic lead. Neurotoxicology 18:201-7
Bourjeily, N; Suszkiw, J B (1997) Developmental cholinotoxicity of lead: loss of septal cholinergic neurons and long-term changes in cholinergic innervation of the hippocampus in perinatally lead-exposed rats. Brain Res 771:319-28
Tian, X; Sun, X; Suszkiw, J B (1996) Developmental age-dependent upregulation of choline acetyltransferase and vesicular acetylcholine transporter mRNA expression in neonatal rat septum by nerve growth factor. Neurosci Lett 209:134-6
Bielarczyk, H; Tian, X; Suszkiw, J B (1996) Cholinergic denervation-like changes in rat hippocampus following developmental lead exposure. Brain Res 708:108-15
Sun, L R; Suszkiw, J B (1995) Extracellular inhibition and intracellular enhancement of Ca2+ currents by Pb2+ in bovine adrenal chromaffin cells. J Neurophysiol 74:574-81
Tian, X; Bourjeily, N; Bielarczyk, H et al. (1995) Reduced densities of sodium-dependent [3H] hemicholinium-3 binding sites in hippocampus of developmental rats following perinatal low-level lead exposure. Brain Res Dev Brain Res 86:268-74
Sun, L R; Suszkiw, J B (1994) Pb2+ activates potassium currents in bovine adrenal chromaffin cells. Neurosci Lett 182:41-3

Showing the most recent 10 out of 11 publications