Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES006754-02
Application #
2155621
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1994-09-01
Project End
1999-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Louisiana State University A&M Col Baton Rouge
Department
Miscellaneous
Type
Schools of Arts and Sciences
DUNS #
075050765
City
Baton Rouge
State
LA
Country
United States
Zip Code
70803
Squadrito, G L; Cueto, R; Splenser, A E et al. (2000) Reaction of uric acid with peroxynitrite and implications for the mechanism of neuroprotection by uric acid. Arch Biochem Biophys 376:333-7
Zhang, H; Squadrito, G L; Uppu, R et al. (1999) Reaction of peroxynitrite with melatonin: A mechanistic study. Chem Res Toxicol 12:526-34
Bolzan, R M; Cueto, R; Squadrito, G L et al. (1999) Direct and simultaneous ultraviolet second-derivative spectrophotometric determination of nitrite and nitrate in preparations of peroxynitrite. Methods Enzymol 301:178-87
Grace, S C; Yamasaki, H; Pryor, W A (1999) Spin stabilizing approach to radical characterization of phenylpropanoid antioxidants: an ESR study of chlorogenic acid oxidation in the horseradish peroxidase, tyrosinase, and ferrylmyoglobin protein radical systems. Basic Life Sci 66:435-50
Salgo, M G; Cueto, R; Winston, G W et al. (1999) Beta carotene and its oxidation products have different effects on microsome mediated binding of benzo[a]pyrene to DNA. Free Radic Biol Med 26:162-73
Kafoury, R M; Pryor, W A; Squadrito, G L et al. (1998) Lipid ozonation products activate phospholipases A2, C, and D. Toxicol Appl Pharmacol 150:338-49
Squadrito, G L; Pryor, W A (1998) The nature of reactive species in systems that produce peroxynitrite. Chem Res Toxicol 11:718-9
Uppu, R M; Lemercier, J N; Squadrito, G L et al. (1998) Nitrosation by peroxynitrite: use of phenol as a probe. Arch Biochem Biophys 358:1-16
Grace, S C; Salgo, M G; Pryor, W A (1998) Scavenging of peroxynitrite by a phenolic/peroxidase system prevents oxidative damage to DNA. FEBS Lett 426:24-8
Zhang, H; Squadrito, G L; Pryor, W A (1998) The reaction of melatonin with peroxynitrite: formation of melatonin radical cation and absence of stable nitrated products. Biochem Biophys Res Commun 251:83-7

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