Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES006839-03
Application #
2155750
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1994-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Medical Br Galveston
Department
Type
Organized Research Units
DUNS #
041367053
City
Galveston
State
TX
Country
United States
Zip Code
77555
Thiviyanathan, Varatharasa; Somasunderam, Anoma; Hazra, Tapas K et al. (2003) Solution structure of a DNA duplex containing 8-hydroxy-2'-deoxyguanosine opposite deoxyguanosine. J Mol Biol 325:433-42
Volk, David E; Thiviyanathan, Varatharasa; Rice, Jeffrey S et al. (2003) Solution structure of a cis-opened (10R)-N6-deoxyadenosine adduct of (9S,10R)-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a DNA duplex. Biochemistry 42:1410-20
Chen, K H; Srivastava, D K; Wilson, S H (2001) Relationship between base excision repair capacity and DNA alkylating agent sensitivity in mouse monocytes. Mutat Res 487:121-6
Peterson, J W; King, D; Ezell, E L et al. (2001) Cholera toxin-induced PGE(2) activity is reduced by chemical reaction with L-histidine. Biochim Biophys Acta 1537:27-41
Volk, D E; Rice, J S; Luxon, B A et al. (2000) NMR evidence for syn-anti interconversion of a trans opened (10R)-dA adduct of benzo[a]pyrene (7S,8R)-diol (9R,10S)-epoxide in a DNA duplex. Biochemistry 39:14040-53
Chen, K H; Yakes, F M; Srivastava, D K et al. (1998) Up-regulation of base excision repair correlates with enhanced protection against a DNA damaging agent in mouse cell lines. Nucleic Acids Res 26:2001-7
Schwartz, J L; Rice, J S; Luxon, B A et al. (1997) Solution structure of the minor conformer of a DNA duplex containing a dG mismatch opposite a benzo[a]pyrene diol epoxide/dA adduct: glycosidic rotation from syn to anti at the modified deoxyadenosine. Biochemistry 36:11069-76
Efrati, E; Tocco, G; Eritja, R et al. (1997) Abasic translesion synthesis by DNA polymerase beta violates the ""A-rule"". Novel types of nucleotide incorporation by human DNA polymerase beta at an abasic lesion in different sequence contexts. J Biol Chem 272:2559-69
Kim, S; Merrill, B M; Rajpurohit, R et al. (1997) Identification of N(G)-methylarginine residues in human heterogeneous RNP protein A1: Phe/Gly-Gly-Gly-Arg-Gly-Gly-Gly/Phe is a preferred recognition motif. Biochemistry 36:5185-92
Prasad, R; Singhal, R K; Srivastava, D K et al. (1996) Specific interaction of DNA polymerase beta and DNA ligase I in a multiprotein base excision repair complex from bovine testis. J Biol Chem 271:16000-7

Showing the most recent 10 out of 19 publications