Rothwell, D G; Hang, B; Gorman, M A et al. (2000) Substitution of Asp-210 in HAP1 (APE/Ref-1) eliminates endonuclease activity but stabilises substrate binding. Nucleic Acids Res 28:2207-13
|
Sagi, J; Chenna, A; Hang, B et al. (1998) A single cyclic p-benzoquinone adduct can destabilize a DNA oligonucleotide duplex. Chem Res Toxicol 11:329-34
|
Hang, B; Singer, B; Margison, G P et al. (1997) Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine. Proc Natl Acad Sci U S A 94:12869-74
|
Hang, B; Rothwell, D G; Sagi, J et al. (1997) Evidence for a common active site for cleavage of an AP site and the benzene-derived exocyclic adduct, 3,N4-benzetheno-dC, in the major human AP endonuclease. Biochemistry 36:15411-8
|
Singer, B; Hang, B (1997) What structural features determine repair enzyme specificity and mechanism in chemically modified DNA? Chem Res Toxicol 10:713-32
|
Hang, B; Chenna, A; Fraenkel-Conrat, H et al. (1996) An unusual mechanism for the major human apurinic/apyrimidinic (AP) endonuclease involving 5' cleavage of DNA containing a benzene-derived exocyclic adduct in the absence of an AP site. Proc Natl Acad Sci U S A 93:13737-41
|
Singer, B (1996) DNA damage: chemistry, repair, and mutagenic potential. Regul Toxicol Pharmacol 23:2-13
|