Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES007612-02
Application #
2157054
Study Section
Special Emphasis Panel (SRC (R))
Project Start
1995-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Virginia Polytechnic Institute and State University
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
003137015
City
Blacksburg
State
VA
Country
United States
Zip Code
24061
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Gogal Jr, R M; Smith, B J; Kalnitsky, J et al. (2000) Analysis of apoptosis of lymphoid cells in fish exposed to immunotoxic compounds. Cytometry 39:310-8
Smith, D A; Schurig, G G; Smith, S A et al. (1999) Tilapia (Oreochromis niloticus) and rodents exhibit similar patterns of inhibited antibody production following exposure to immunotoxic chemicals. Vet Hum Toxicol 41:368-73
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Hart, L J; Smith, S A; Smith, B J et al. (1997) Exposure of tilapian fish to the pesticide lindane results in hypocellularity of the primary hematopoietic organ (pronephros) and the spleen without altering activity of phagocytic cells in these organs. Toxicology 118:211-21
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Orner, G A; Donohoe, R M; Hendricks, J D et al. (1996) Comparison of the enhancing effects of dehydroepiandrosterone with the structural analog 16 alpha-fluoro-5-androsten-17-one on aflatoxin B1 hepatocarcinogenesis in rainbow trout. Fundam Appl Toxicol 34:132-40
Orner, G A; Mathews, C; Hendricks, J D et al. (1995) Dehydroepiandrosterone is a complete hepatocarcinogen and potent tumor promoter in the absence of peroxisome proliferation in rainbow trout. Carcinogenesis 16:2893-8
Kelly, J D; Orner, G A; Hendricks, J D et al. (1992) Dietary hydrogen peroxide enhances hepatocarcinogenesis in trout: correlation with 8-hydroxy-2'-deoxyguanosine levels in liver DNA. Carcinogenesis 13:1639-42