Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES007687-02
Application #
2157138
Study Section
Special Emphasis Panel (SRC (R))
Project Start
1995-08-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
West Virginia University
Department
Pathology
Type
Schools of Dentistry
DUNS #
191510239
City
Morgantown
State
WV
Country
United States
Zip Code
26506
Kim, D; Somji, S; Garrett, S H et al. (2001) Expression of hsp 27, hsp 60, hsc 70, and hsp 70 by immortalized human proximal tubule cells (HK-2) following exposure to heat shock, sodium arsenite, or cadmium chloride. J Toxicol Environ Health A 63:475-93
Garrett, S H; Belcastro, M; Sens, M A et al. (2001) Acute exposure to arsenite induces metallothionein isoform-specific gene expression in human proximal tubule cells. J Toxicol Environ Health A 64:343-55
Somji, S; Todd, J H; Sens, M A et al. (2000) Expression of heat shock protein 60 in human proximal tubule cells exposed to heat, sodium arsenite and CdCl(2). Toxicol Lett 115:127-36
Garrett, S H; Sens, M A; Todd, J H et al. (1999) Expression of MT-3 protein in the human kidney. Toxicol Lett 105:207-14
Somji, S; Todd, J H; Sens, M A et al. (1999) Expression of the constitutive and inducible forms of heat shock protein 70 in human proximal tubule cells exposed to heat, sodium arsenite, and CdCl(2). Environ Health Perspect 107:887-93
Somji, S; Sens, D A; Garrett, S H et al. (1999) Heat shock protein 27 expression in human proximal tubule cells exposed to lethal and sublethal concentrations of CdCl2. Environ Health Perspect 107:545-52
Garrett, S H; Somji, S; Todd, J H et al. (1998) Differential expression of human metallothionein isoform I mRNA in human proximal tubule cells exposed to metals. Environ Health Perspect 106:825-31
Friedline, J A; Garrett, S H; Somji, S et al. (1998) Differential expression of the MT-1E gene in estrogen-receptor-positive and -negative human breast cancer cell lines. Am J Pathol 152:23-7
Garrett, S H; Somji, S; Todd, J H et al. (1998) Exposure of human proximal tubule cells to cd2+, zn2+, and Cu2+ induces metallothionein protein accumulation but not metallothionein isoform 2 mRNA. Environ Health Perspect 106:587-95
Hoey, J G; Garrett, S H; Sens, M A et al. (1997) Expression of MT-3 mRNA in human kidney, proximal tubule cell cultures, and renal cell carcinoma. Toxicol Lett 92:149-60

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