The long-term objective of this application is to develop and test a set of tools and procedures for spatio-temporal analysis of environmental health data in a GIS framework. Current commercial geographic information systems have very little capability to handle aspects of geographic information. Temporal data is critical to understanding environmental health, especially for effects with long latency periods.
Specific aims are to define appropriate data models and query languages, as well as logical operations, for handling geospatial lifelines, which ideally are continuous time-stamped records of people's positions in geographic space. Methods for visualization, generalization, and handling missing data all will be developed and tested. These methods will allow researchers to roll back residential locations of people who are cases of some health problem, to discover whether they were more strongly clustered at times in the past than they are today. This could counteract the tendency for human migration and mobility to break up and thus mask geographical clusters of cases for conditions that have long latency periods. While the core concepts of this project will involve collections of individual-level data, we also will examine how aggregate data can be used to address some of the same issues. The project also will investigate implications of the availability of such analysis, database, and reasoning procedures for personal and data privacy. Existing methods for interpolating and visualizing three-dimensional data will be adapted to deal with representations of environmental measures as functions of two spatial and one temporal dimension. We will then develop methods to efficiently intersect individual geospatial lifelines with such fields representing environmental hazards or toxins, to determine which individuals are likely to have been exposed, and to estimate both maximum and cumulative exposure levels. The project also will determine methods for efficiently finding geospatial lifelines most similar to a given one, so that geospatial life history can be controlled for in case-control studies.

Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES009816-03
Application #
6382292
Study Section
Social Sciences and Population Study Section (SSP)
Program Officer
Gray, Kimberly A
Project Start
1999-06-01
Project End
2003-05-31
Budget Start
2001-06-01
Budget End
2002-05-31
Support Year
3
Fiscal Year
2001
Total Cost
$401,225
Indirect Cost
Name
State University of New York at Buffalo
Department
Miscellaneous
Type
Schools of Arts and Sciences
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260
Han, Daikwon; Bonner, Matthew R; Nie, Jing et al. (2011) The use of birth certificate data to reconstruct and validate self-reported birth address in a study of breast cancer and environment. Ann Epidemiol 21:710-3
Bove Jr, Gerald E; Rogerson, Peter A; Vena, John E (2007) Case control study of the geographic variability of exposure to disinfectant byproducts and risk for rectal cancer. Int J Health Geogr 6:18
Rogerson, Peter A; Sinha, Gaurav; Han, Daikwon (2006) Recent changes in the spatial pattern of prostate cancer in the U.S. Am J Prev Med 30:S50-9
Rogerson, Peter A (2006) Statistical methods for the detection of spatial clustering in case-control data. Stat Med 25:811-23
Bonner, Matthew R; Han, Daikwon; Nie, Jing et al. (2005) Breast cancer risk and exposure in early life to polycyclic aromatic hydrocarbons using total suspended particulates as a proxy measure. Cancer Epidemiol Biomarkers Prev 14:53-60
Rogerson, Peter A; Yamada, I (2004) Approaches to syndromic surveillance when data consist of small regional counts. MMWR Morb Mortal Wkly Rep 53 Suppl:79-85
Rogerson, Peter A; Yamada, Ikuho (2004) Monitoring change in spatial patterns of disease: comparing univariate and multivariate cumulative sum approaches. Stat Med 23:2195-214
Han, Daikwon; Rogerson, Peter A; Nie, Jing et al. (2004) Geographic clustering of residence in early life and subsequent risk of breast cancer (United States). Cancer Causes Control 15:921-9
Henry, Jade Vu; Magruder, S; Snyder, M (2004) Comparison of office visit and nurse advice hotline data for syndromic surveillance--Baltimore-Washington, D.C., metropolitan area, 2002. MMWR Morb Mortal Wkly Rep 53 Suppl:112-6
Rogerson, Peter A; Han, Daikwon (2002) The effects of migration on the detection of geographic differences in disease risk. Soc Sci Med 55:1817-28