Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
5R01ES011633-02
Application #
6659676
Study Section
Chemical Pathology Study Section (CPA)
Program Officer
Mcallister, Kimberly A
Project Start
2002-09-15
Project End
2007-07-31
Budget Start
2003-08-01
Budget End
2004-07-31
Support Year
2
Fiscal Year
2003
Total Cost
$388,750
Indirect Cost
Name
Rutgers University
Department
Genetics
Type
Schools of Arts and Sciences
DUNS #
001912864
City
New Brunswick
State
NJ
Country
United States
Zip Code
08901
Xu, Bing; Wang, Wenxing; Guo, Haiyang et al. (2014) Oxidative stress preferentially induces a subtype of micronuclei and mediates the genomic instability caused by p53 dysfunction. Mutat Res 770:1-8
Tichy, Elisia D; Pillai, Resmi; Deng, Li et al. (2012) The abundance of Rad51 protein in mouse embryonic stem cells is regulated at multiple levels. Stem Cell Res 9:124-34
Liu, Yanguo; Deng, Li; Nguyen, Son C et al. (2012) A human cell-based reporter detects microhomology-mediated end joining. Mutat Res 731:140-4
Rani, Vamsi; Neumann, Carola A; Shao, Changshun et al. (2012) Prdx1 deficiency in mice promotes tissue specific loss of heterozygosity mediated by deficiency in DNA repair and increased oxidative stress. Mutat Res 735:39-45
Tichy, Elisia D; Liang, Li; Deng, Li et al. (2011) Mismatch and base excision repair proficiency in murine embryonic stem cells. DNA Repair (Amst) 10:445-51
Denissova, Natalia G; Tereshchenko, Irina V; Cui, Eric et al. (2011) Ionizing radiation is a potent inducer of mitotic recombination in mouse embryonic stem cells. Mutat Res 715:1-6
Serrano, Lourdes; Liang, Li; Chang, Yiming et al. (2011) Homologous recombination conserves DNA sequence integrity throughout the cell cycle in embryonic stem cells. Stem Cells Dev 20:363-74
Tereshchenko, Irina V; Chen, Yanping; McDaniel, Lisa D et al. (2010) Small scale genetic alterations contribute to increased mutability at the X-linked Hprt locus in vivo in Blm hypomorphic mice. DNA Repair (Amst) 9:551-7
Shao, Changshun; Liang, Li; Zhao, Xin et al. (2009) Mutagenesis in vivo in T cells of p21-deficient mice. Mutat Res 670:103-6
Barrera-Oro, Julio; Liu, Tzu-Yang; Gorden, Erin et al. (2008) Role of the mismatch repair gene, Msh6, in suppressing genome instability and radiation-induced mutations. Mutat Res 642:74-9

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