Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Research Project (R01)
Project #
3R01ES011662-01S1
Application #
6683529
Study Section
Alcohol and Toxicology Subcommittee 4 (ALTX)
Program Officer
Lawler, Cindy P
Project Start
2002-03-27
Project End
2006-02-28
Budget Start
2002-11-22
Budget End
2003-02-28
Support Year
1
Fiscal Year
2003
Total Cost
$20,355
Indirect Cost
Name
Michigan State University
Department
Pharmacology
Type
Schools of Veterinary Medicine
DUNS #
193247145
City
East Lansing
State
MI
Country
United States
Zip Code
48824
Tsai, Tidao; Yuan, Yukun; Hajela, Ravindra K et al. (2017) Methylmercury induces an initial increase in GABA-evoked currents in Xenopus oocytes expressing ?1and ?6subunit-containing GABAAreceptors. Neurotoxicology 60:161-170
Yuan, Yukun; Atchison, William D (2016) Multiple Sources of Ca2+ Contribute to Methylmercury-Induced Increased Frequency of Spontaneous Inhibitory Synaptic Responses in Cerebellar Slices of Rat. Toxicol Sci 150:117-30
Limke, Tobi L; Atchison, William D (2009) Application of single-cell microfluorimetry to neurotoxicology assays. Curr Protoc Toxicol Chapter 12:Unit 12.15
Herden, Christina J; Pardo, Nicole E; Hajela, Ravindra K et al. (2008) Differential effects of methylmercury on gamma-aminobutyric acid type A receptor currents in rat cerebellar granule and cerebral cortical neurons in culture. J Pharmacol Exp Ther 324:517-28
Yuan, Yukun; Atchison, William D (2007) Methylmercury-induced increase of intracellular Ca2+ increases spontaneous synaptic current frequency in rat cerebellar slices. Mol Pharmacol 71:1109-21
Yuan, Yukun; Atchison, William D (2005) Methylmercury induces a spontaneous, transient slow inward chloride current in Purkinje cells of rat cerebellar slices. J Pharmacol Exp Ther 313:751-64
Atchison, William D (2005) Is chemical neurotransmission altered specifically during methylmercury-induced cerebellar dysfunction? Trends Pharmacol Sci 26:549-57
Yuan, Yukun; Otero-Montanez, James K L; Yao, Aizhen et al. (2005) Inwardly rectifying and voltage-gated outward potassium channels exhibit low sensitivity to methylmercury. Neurotoxicology 26:439-54
Yuan, Yukun; Atchison, William D (2003) Methylmercury differentially affects GABA(A) receptor-mediated spontaneous IPSCs in Purkinje and granule cells of rat cerebellar slices. J Physiol 550:191-204