This project is proceeding along two lines, both concerning glaucoma. The one line is to measure the resistances of various portions of the tortuous path by which fluid leaves the eye; by doing this we will be able to target our investigations to the particular structures offering major resistance to fluid outflow and thus most probably causing glaucoma. The second line of investigation is a study of the reaction of the living eye to a small, abrupt rise in intraocular pressure. This is accomplished by pressing a flat surface against the cornea, thus displacing fluid from a portion of the corneal dome. The area of the flattened corneal surface is kept constant while the intraocular pressure is continuously measured for four minutes. In most cases there are two findings of note: (1) the pressure returns to the """"""""resting"""""""" pessure within four minutes, and (2) the intraocular pressure after four minutes of the procedure is often lower than the """"""""resting"""""""" pressure. We will be tesing to see if this procedure helps to separate those eyes with harmless high """"""""resting"""""""" pressure from those eyes prone to develop glaucoma.
| Roberts, D A (1987) Analysis of vessel absorption profiles in retinal oximetry. Med Phys 14:124-30 |
| Moses, R A; Schmoll, D W; Dihenia, B (1986) The effect of iloprost on the rabbit eye. J Ocul Pharmacol 2:147-9 |
| Moses, R A; Goldberg, I (1986) Pilocarpine-induced movement of the trabecular mesh. Aust N Z J Ophthalmol 14:333-7 |
| Moses, R A; Grodzki Jr, W J (1985) Mechanism of glaucoma secondary to increased venous pressure. Arch Ophthalmol 103:1701-3 |
| Moses, R A; Grodzki Jr, W J; Carras, P L (1985) Pseudofacility. Where did it go? Arch Ophthalmol 103:1653-5 |
| Ruben, J B; Moses, R A; Grodzki Jr, W J (1985) Perfusion outflow facility in the rabbit eye. Stabilization by EACA. Invest Ophthalmol Vis Sci 26:153-8 |
| Moses, R A; Brown, D N (1985) Short-term re-epithelialization of the alkali-burned rabbit cornea. Ann Ophthalmol 17:714-6 |
