We have shown that with field sizes of 8 degrees or more, protanopes and deuteranopes have trichromatic vision, mediated by a rhodopsin photorecptor. We propose a full delineation of this large-field trichromacy, and a comparison of large-field trichromacy with small-field dichromacy. In addition, we plan to study observers who show evidence of a rhodopsin-mediated color vision system, namely the incomplete achromats. We will perform psychophysical studies using fields of 1 degree to 8 degrees visual angle. The specific studies we propose include: color matching, luminosity (by heterochromactic flicker photometry), wavelength discrimination, hue estimation, and threshold additivity.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY001876-10
Application #
3256280
Study Section
(SSS)
Project Start
1977-09-30
Project End
1987-09-29
Budget Start
1986-09-30
Budget End
1987-09-29
Support Year
10
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Chicago
Department
Type
Schools of Medicine
DUNS #
225410919
City
Chicago
State
IL
Country
United States
Zip Code
60637
Felleman, Daniel J; Lim, Heejin; Xiao, Youping et al. (2015) The Representation of Orientation in Macaque V2: Four Stripes Not Three. Cereb Cortex 25:2354-69
Schutte, M; Werner, P (1998) Redistribution of glutathione in the ischemic rat retina. Neurosci Lett 246:53-6
Lutze, M; Cox, N J; Smith, V C et al. (1990) Genetic studies of variation in Rayleigh and photometric matches in normal trichromats. Vision Res 30:149-62
Yeh, T; Smith, V C; Pokorny, J (1989) The effect of background luminance on cone sensitivity functions. Invest Ophthalmol Vis Sci 30:2077-86
Bresnick, G H; Smith, V C; Pokorny, J (1989) Autosomal dominantly inherited macular dystrophy with preferential short-wavelength sensitive cone involvement. Am J Ophthalmol 108:265-76
Khouri, G; Mets, M B; Smith, V C et al. (1988) X-linked congenital stationary night blindness. Review and report of a family with hyperopia. Arch Ophthalmol 106:1417-22
Sawusch, M; Pokorny, J; Smith, V C (1987) Clinical electroretinography for short wavelength sensitive cones. Invest Ophthalmol Vis Sci 28:966-74
Pokorny, J; Smith, V C (1986) Eye disease and color defects. Vision Res 26:1573-84
Smith, V C; Pokorny, J; Pass, A S (1985) Color-axis determination on the Farnsworth-Munsell 100-hue test. Am J Ophthalmol 100:176-82