Rabbit lenses will be incubated in organ culture with 14C acetate. Incorporation into the various classes of lipids and individual fatty acids will be determined. Studies will be duplicated on glucose induced cataracts.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY003190-06
Application #
3257483
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1980-04-01
Project End
1988-09-29
Budget Start
1986-09-30
Budget End
1988-09-29
Support Year
6
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Tennessee Technological University
Department
Type
Schools of Arts and Sciences
DUNS #
City
Cookeville
State
TN
Country
United States
Zip Code
38501
Swindell, R T; Harris, H; Buchanan, L et al. (1988) Ganglioside composition in human cataractous nuclei. Ophthalmic Res 20:232-6
Albers-Jackson, B; Nga Do, A (1987) Lipid synthesis in the bovine lens. Curr Eye Res 6:1161-4
Swindell, R T; Bell, V C; Slaughter, S et al. (1987) Incorporation of 14C-galactose into gangliosides of rabbit lens. Curr Eye Res 6:451-6
Albers-Jackson, B; Sun, H Y (1985) Incorporation of 14C acetate into lipids of the ICR mouse lens. Curr Eye Res 4:1281-7