Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY004939-14
Application #
2159216
Study Section
Special Emphasis Panel (ZRG1-VISB (01))
Project Start
1983-08-01
Project End
1997-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Medical University of South Carolina
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425
Bowrey, Hannah E; Anderson, David M; Pallitto, Patrick et al. (2016) Imaging mass spectrometry of the visual system: Advancing the molecular understanding of retina degenerations. Proteomics Clin Appl 10:391-402
Tang, Peter H; Crouch, Rosalie K (2015) Sustained delivery of retinoids to prevent photoreceptor death. Methods Mol Biol 1271:363-8
Crouch, Rosalie K; Koutalos, Yiannis; Kono, Masahiro et al. (2015) A2E and Lipofuscin. Prog Mol Biol Transl Sci 134:449-63
Ablonczy, Zsolt; Smith, Noah; Anderson, David M et al. (2014) The utilization of fluorescence to identify the components of lipofuscin by imaging mass spectrometry. Proteomics 14:936-44
Ablonczy, Zsolt; Higbee, Daniel; Grey, Angus C et al. (2013) Similar molecules spatially correlate with lipofuscin and N-retinylidene-N-retinylethanolamine in the mouse but not in the human retinal pigment epithelium. Arch Biochem Biophys 539:196-202
Ablonczy, Zsolt; Higbee, Daniel; Anderson, David M et al. (2013) Lack of correlation between the spatial distribution of A2E and lipofuscin fluorescence in the human retinal pigment epithelium. Invest Ophthalmol Vis Sci 54:5535-42
Tang, Peter H; Kono, Masahiro; Koutalos, Yiannis et al. (2013) New insights into retinoid metabolism and cycling within the retina. Prog Retin Eye Res 32:48-63
Bandyopadhyay, Mausumi; Kono, Masahiro; Rohrer, Bärbel (2013) Explant cultures of Rpe65-/- mouse retina: a model to investigate cone opsin trafficking. Mol Vis 19:1149-57
Frederiksen, Rikard; Boyer, Nicholas P; Nickle, Benjamin et al. (2012) Low aqueous solubility of 11-cis-retinal limits the rate of pigment formation and dark adaptation in salamander rods. J Gen Physiol 139:493-505
Boyer, Nicholas P; Tang, Peter H; Higbee, Daniel et al. (2012) Lipofuscin and A2E accumulate with age in the retinal pigment epithelium of Nrl-/- mice. Photochem Photobiol 88:1373-7

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