Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY005895-12
Application #
2159640
Study Section
Visual Sciences A Study Section (VISA)
Project Start
1984-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1997-11-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Yamane, H K; Fung, B K (1993) Covalent modifications of G-proteins. Annu Rev Pharmacol Toxicol 33:201-41
Lee, R H; Lieberman, B S; Yamane, H K et al. (1992) A third form of the G protein beta subunit. 1. Immunochemical identification and localization to cone photoreceptors. J Biol Chem 267:24776-81
Fung, B K; Lieberman, B S; Lee, R H (1992) A third form of the G protein beta subunit. 2. Purification and biochemical properties. J Biol Chem 267:24782-8
Anant, J S; Ong, O C; Xie, H Y et al. (1992) In vivo differential prenylation of retinal cyclic GMP phosphodiesterase catalytic subunits. J Biol Chem 267:687-90
Yamane, H K; Farnsworth, C C; Xie, H Y et al. (1991) Membrane-binding domain of the small G protein G25K contains an S-(all-trans-geranylgeranyl)cysteine methyl ester at its carboxyl terminus. Proc Natl Acad Sci U S A 88:286-90
Fung, B K; Yamane, H K; Ota, I M et al. (1990) The gamma subunit of brain G-proteins is methyl esterified at a C-terminal cysteine. FEBS Lett 260:313-7
Yamane, H K; Farnsworth, C C; Xie, H Y et al. (1990) Brain G protein gamma subunits contain an all-trans-geranylgeranylcysteine methyl ester at their carboxyl termini. Proc Natl Acad Sci U S A 87:5868-72
Fung, B K; Young, J H; Yamane, H K et al. (1990) Subunit stoichiometry of retinal rod cGMP phosphodiesterase. Biochemistry 29:2657-64
Ong, O C; Ota, I M; Clarke, S et al. (1989) The membrane binding domain of rod cGMP phosphodiesterase is posttranslationally modified by methyl esterification at a C-terminal cysteine. Proc Natl Acad Sci U S A 86:9238-42
Griswold-Prenner, I; Tuteja, N; Farber, D B et al. (1989) G protein-effector coupling: interactions of recombinant inhibitory gamma subunit with transducin and phosphodiesterase. Biochemistry 28:6145-50

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