Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY007543-08
Application #
2161538
Study Section
Visual Sciences C Study Section (VISC)
Project Start
1988-03-01
Project End
1999-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Medical University of South Carolina
Department
Pathology
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425
Corson, D Wesley; Pepperberg, David R (2003) Conditioning light differentially desensitizes rod phototransduction mediated by native and 9-demethyl analog visual pigment. Vis Neurosci 20:29-36
Ma, J; Znoiko, S; Othersen, K L et al. (2001) A visual pigment expressed in both rod and cone photoreceptors. Neuron 32:451-61
Corson, D W; Kefalov, V J; Cornwall, M C et al. (2000) Effect of 11-cis 13-demethylretinal on phototransduction in bleach-adapted rod and cone photoreceptors. J Gen Physiol 116:283-97
Li, Z; Zhuang, J; Corson, D W (1999) Delivery of 9-Cis retinal to photoreceptors from bovine serum albumin. Photochem Photobiol 69:500-4
Martinez, L M; Crouch, R K; Corson, D W (1997) Application of a submicroliter spectrophotometer in visual pigment studies. Mol Vis 3:4
Chen, N; Ma, J X; Corson, D W et al. (1996) Molecular cloning of a rhodopsin gene from salamander rods. Invest Ophthalmol Vis Sci 37:1907-13
Corson, D W; Crouch, R K (1996) Physiological activity of retinoids in natural and artificial visual pigments. Photochem Photobiol 63:595-600
Corson, D W; Cornwall, M C; Pepperberg, D R (1994) Evidence for the prolonged photoactivated lifetime of an analogue visual pigment containing 11-cis 9-desmethylretinal. Vis Neurosci 11:91-8
Corson, D W; Cornwall, M C; MacNichol, E F et al. (1994) Relief of opsin desensitization and prolonged excitation of rod photoreceptors by 9-desmethylretinal. Proc Natl Acad Sci U S A 91:6958-62
Jin, J; Crouch, R K; Corson, D W et al. (1993) Noncovalent occupancy of the retinal-binding pocket of opsin diminishes bleaching adaptation of retinal cones. Neuron 11:513-22

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