.) The long term goal of the research is to develop a noninvasive, objective method for evaluating color vision. The method of study is based on the observation that (in addition to its responses to changes in stimulus luminance), the pupil of the eye produces a transient constriction to isoluminant chromatic stimulus exchanges. The pupil constricts, for example, if a red spot is replaced by an isoluminant green spot and vice versa.
The specific aims are to set up a laboratory for studying these transient pupillary responses in adult observers, to study the response evoked by stimuli of various chromaticities, to investigate the relationship between response magnitude and such factors as stimulus size and retinal eccentricity, to test whether the spatial pattern within the stimulus field affects the response, to determine how chromatic and luminance components of the pupillary response combine, and to determine the contribution of rods to the transient pupillary response. Research of such pupillary responses may lead to new alternatives in the clinical evaluation of visual abnormalities, in the evaluation of the visual status of noncommunicative or cognitive-impaired subjects, in the study of the visual development of infants or in the psychophysical study of animal vision.

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Research Project (R01)
Project #
5R01EY008384-02
Application #
3265689
Study Section
Visual Sciences B Study Section (VISB)
Project Start
1991-03-01
Project End
1996-02-29
Budget Start
1992-03-01
Budget End
1993-02-28
Support Year
2
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Texas Tech University
Department
Type
Schools of Medicine
DUNS #
609980727
City
Lubbock
State
TX
Country
United States
Zip Code
79430
Kimura, E; Young, R S (1999) S-cone contribution to pupillary responses evoked by chromatic flash offset. Vision Res 39:1189-97
Kimura, E; Young, R S (1996) A chromatic-cancellation property of human pupillary responses. Vision Res 36:1543-50
Kimura, E; Young, R S (1995) Nature of the pupillary responses evoked by chromatic flashes on a white background. Vision Res 35:897-906
Young, R S; Kimura, E; Delucia, P R (1995) A pupillometric correlate of scotopic visual acuity. Vision Res 35:2235-41
Young, R S; Han, B C; Wu, P Y (1993) Transient and sustained components of the pupillary responses evoked by luminance and color. Vision Res 33:437-46
Young, R S; Kennish, J (1993) Transient and sustained components of the pupil response evoked by achromatic spatial patterns. Vision Res 33:2239-52